DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UBQLNL and CG31528

DIOPT Version :9

Sequence 1:	NP_659490.4	Gene:	UBQLNL / 143630	HGNCID:	28294	Length:	475	Species:	Homo sapiens
Sequence 2:	NP_730833.1	Gene:	CG31528 / 318785	FlyBaseID:	FBgn0051528	Length:	344	Species:	Drosophila melanogaster

Alignment Length:	399	Identity:	86/399 - (21%)
Similarity:	145/399 - (36%)	Gaps:	130/399 - (32%)

- Green bases have known domain annotations that are detailed below.

Human    33 VIVKTAGNQKDFMVADDISVRQFKEMLLAHFQCQMDQLVLVFMGCLLKDHDTLSQRGIMDGHTIY 97
            :..|.:|..:...:..:..:|..:.::...|:..:.:::|||.|.:|.|..|:..|||:.|.|::
  Fly     9 ICAKGSGRVETVTLRQNELIRNLRVLVAVRFEQAISRIILVFAGQVLSDEGTIDSRGIVSGVTVH 73

Human    98 LVI-----------------KSKQGSRSL-----AH---------SFRDLPTNDPCHRDRNTKGN 131
            :|.                 :||...|.:     ||         ..|.|...||
  Fly    74 VVCRAEAANSPSPTPIAATKRSKPSERLMRSWQSAHIAFLQQEPDVLRSLLQADP---------- 128

Human   132 SSRVHQPTGMNQAPVELAHFVGSDAPKVHTQNLEVSHPECKAQMLE---NPSIQRL-------LS 186
              |:......|.|   :.|::.||      |||.        :||.   :|:.|.|       :|
  Fly   129 --RIRSLLDENAA---MRHYLNSD------QNLR--------EMLSLAFSPAKQELGRRRDLHIS 174

Human   187 NMEFMWQFISEHLDTQQLMQQNPEVSRLLLDNSEILLQTLELARNLAMIQEIMQIQQPSQNLEYP 251
            .|||:                 |...::|...:..:||..|  .|:|     |..||.||..:..
  Fly   175 RMEFV-----------------PGGYKVLSRLNYCMLQAYE--DNVA-----MAFQQASQGAKTS 215

Human   252 LNPQPYLGLETMPGGNNALGQNYADINDQMLNS-MQDPFGGNPFTALLAGQV---LEQVQSSPPP 312
            .|||  .|||               :.|.:.|. ::.|...||.|..|..:|   ...|:.|.|.
  Fly   216 SNPQ--RGLE---------------VKDPLPNPWLRMPRIRNPRTCALPRRVNKGRSSVKQSDPN 263

Human   313 PPPSQEQQDQLTQHPATRVIYNS--SGG-------FSSNTSANDTLNKVNHTSKANT--AMISTK 366
            ....|:...::....||:.....  |||       :.|..   :.|.::.:::::..  |::.:.
  Fly   264 ADCRQKSSSKVMTSTATQTKCKDRRSGGDGHCQHCYQSQV---EQLTQMGYSNRSRNKRALLISL 325

Human   367 GQSHICATR 375
            |... ||.|
  Fly   326 GNVD-CAVR 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UBQLNL	NP_659490.4	UBQ	32..101	CDD:214563	17/84 (20%)
		UBQ	32..101	CDD:294102	17/84 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..138		5/24 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..325		4/19 (21%)
CG31528	NP_730833.1	UBQ	7..77	CDD:294102	17/67 (25%)
CG31528	NP_730833.1	UBA_like_SF	299..335	CDD:304366	7/39 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148236
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1553668at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10677
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850