| Sequence 1: | NP_067432.2 | Gene: | Fzd1 / 14362 | MGIID: | 1196625 | Length: | 642 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001261836.1 | Gene: | fz / 45307 | FlyBaseID: | FBgn0001085 | Length: | 612 | Species: | Drosophila melanogaster |
| Alignment Length: | 584 | Identity: | 276/584 - (47%) |
|---|---|---|---|
| Similarity: | 355/584 - (60%) | Gaps: | 66/584 - (11%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 78 SGPGQQAPPPPQPQQSGQQYNGERGISIPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAG 142
Mouse 143 LEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDT 207
Mouse 208 LKCEKFPVHGAGELCVGQNT----SDKGTPTPSLLP------EFWTSNPQHGGGGYRGGYPGGAG 262
Mouse 263 TVERGKFSCPRALRVPSYLNYHF-LGEK---DCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSV 323
Mouse 324 LCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAE------ 382
Mouse 383 -DGARTVAQGTKK-EGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLA 445
Mouse 446 AWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFR 510
Mouse 511 IRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIP 575
Mouse 576 CPHLQGGGGVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGE 639 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Fzd1 | NP_067432.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 26..45 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 76..99 | 6/20 (30%) | |||
| CRD_FZ1 | 107..233 | CDD:143574 | 77/129 (60%) | ||
| 7tmF_FZD1 | 294..641 | CDD:320375 | 173/354 (49%) | ||
| TM helix 1 | 313..338 | CDD:320375 | 13/24 (54%) | ||
| TM helix 2 | 347..368 | CDD:320375 | 11/20 (55%) | ||
| TM helix 3 | 398..424 | CDD:320375 | 13/25 (52%) | ||
| TM helix 4 | 441..457 | CDD:320375 | 11/15 (73%) | ||
| TM helix 5 | 479..508 | CDD:320375 | 14/28 (50%) | ||
| TM helix 6 | 528..555 | CDD:320375 | 14/26 (54%) | ||
| TM helix 7 | 591..616 | CDD:320375 | 11/24 (46%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 620..625 | 2/4 (50%) | |||
| PDZ-binding | 640..642 | 276/584 (47%) | |||
| fz | NP_001261836.1 | CRD_FZ1_like | 51..167 | CDD:143567 | 73/116 (63%) |
| Frizzled | 237..564 | CDD:279827 | 165/330 (50%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 158 | 1.000 | Domainoid score | I4103 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H20750 | |
| Inparanoid | 1 | 1.050 | 528 | 1.000 | Inparanoid score | I1213 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG48699 | |
| OrthoDB | 1 | 1.010 | - | - | D167933at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001848 | |
| OrthoInspector | 1 | 1.000 | - | - | otm43585 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104642 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11309 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3233 |
| SonicParanoid | 1 | 1.000 | - | - | X126 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 15 | 14.870 | |||||