Sequence 1: | NP_067432.2 | Gene: | Fzd1 / 14362 | MGIID: | 1196625 | Length: | 642 | Species: | Mus musculus |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001262037.1 | Gene: | fz2 / 40090 | FlyBaseID: | FBgn0016797 | Length: | 806 | Species: | Drosophila melanogaster |
Alignment Length: | 658 | Identity: | 279/658 - (42%) |
---|---|---|---|
Similarity: | 362/658 - (55%) | Gaps: | 127/658 - (19%) |
- Green bases have known domain annotations that are detailed below.
Mouse 53 GLLLLLWLLEA--PLLLGVRAQAAGQVSGPGQQAPPPPQPQQSGQQYNGERGISIP-----DHGY 110
Mouse 111 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVL 175
Mouse 176 E---QALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHG-AGELCV------------- 223
Mouse 224 --GQNTSDKGTPTPSLLPEFWTSNPQHGGGGYRGGYPGGAGTVE----RGKFS------------ 270
Mouse 271 ---CPRALRVPS------------------------YLN---YHFLGEKDCGAPCEPTKVYGLMY 305
Mouse 306 FGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIA-GFL 369
Mouse 370 LEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEA 434
Mouse 435 IEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTS 499
Mouse 500 FLLAGFVSLFRIRTIMKHD-----GTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQ 559
Mouse 560 WERSWVAQSCKSYAIPCPHLQGGGGVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNS 624
Mouse 625 WRKFYTRL 632 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Fzd1 | NP_067432.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 26..45 | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 76..99 | 5/22 (23%) | |||
CRD_FZ1 | 107..233 | CDD:143574 | 65/144 (45%) | ||
7tmF_FZD1 | 294..641 | CDD:320375 | 182/345 (53%) | ||
TM helix 1 | 313..338 | CDD:320375 | 12/24 (50%) | ||
TM helix 2 | 347..368 | CDD:320375 | 13/21 (62%) | ||
TM helix 3 | 398..424 | CDD:320375 | 18/25 (72%) | ||
TM helix 4 | 441..457 | CDD:320375 | 8/15 (53%) | ||
TM helix 5 | 479..508 | CDD:320375 | 21/28 (75%) | ||
TM helix 6 | 528..555 | CDD:320375 | 22/26 (85%) | ||
TM helix 7 | 591..616 | CDD:320375 | 13/24 (54%) | ||
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 620..625 | 3/4 (75%) | |||
PDZ-binding | 640..642 | ||||
fz2 | NP_001262037.1 | CRD_FZ5_like | 63..182 | CDD:143565 | 62/120 (52%) |
Frizzled | 308..618 | CDD:279827 | 178/330 (54%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X126 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |