Protein Alignment MAPK14 and p38b

DIOPT Version :9

• Sequence 1: XP_011512612.2
• Gene: MAPK14 / 1432
• HGNCID: 6876
• Length: 401
• Species: Homo sapiens
• Sequence 2: NP_477361.1
• Gene: p38b / 34780
• FlyBaseID: FBgn0024846
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 329
• Identity: 230/329 - (69%)
• Similarity: 265/329 - (80%)
• Gaps: 11/329 - (3%)

Human    66 GMRSTVCSTQVRCESAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDV 130
            |....||...||        .|..:||:|||:|||||.:|||||||||||||||.||||||||||
  Fly    33 GAYGQVCKAVVR--------GTSTKVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDV 89

Human   131 F---TPARSLEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDL 192
            |   .||.||::|..||:|||||.||||||::.|||:|||||||:|||||||||||||.:|||||
  Fly    90 FHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDDHVQFLVYQILRGLKYIHSAGVIHRDL 154

Human   193 KPSNLAVNEDCELKILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAEL 257
            ||||:||||||||:||||||||..:.||||||||||||||||||||||||||.||||||||||||
  Fly   155 KPSNIAVNEDCELRILDFGLARPAESEMTGYVATRWYRAPEIMLNWMHYNQTADIWSVGCIMAEL 219

Human   258 LTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLA 322
            |||||||||||||.||.||:.::|||..|.:.:||||||||||:||..||:.||.::|.||||||
  Fly   220 LTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRISSESARNYIRSLPVMPRRNFRDIFRGANPLA 284

Human   323 VDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVI 387
            :|||||||.||:||||||.|||||.|..:||||.||..|..||||||..:|.:::|:.:.:.||.
  Fly   285 IDLLEKMLELDADKRITAEQALAHPYMEKYHDPTDEQTAALYDQSFEENELPVEKWREMVFSEVT 349

Human   388 SFVP 391
            :|.|
  Fly   350 AFKP 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK14	XP_011512612.2	None
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	229/327 (70%)
		S_TKc	24..311	CDD:214567	210/285 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146819
Domainoid	1	1.000	453	1.000	Domainoid score	I508
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31777
Inparanoid	1	1.050	523	1.000	Inparanoid score	I1260
Isobase	1	0.950	-	0	Normalized mean entropy	S378
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	1	1.000	-	-		FOG0000533
OrthoInspector	1	1.000	-	-		mtm8496
orthoMCL	1	0.900	-	-		OOG6_102675
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R566
SonicParanoid	1	1.000	-	-		X352
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.740