Protein Alignment MAPK14 and rl

DIOPT Version :9

• Sequence 1: XP_011512612.2
• Gene: MAPK14 / 1432
• HGNCID: 6876
• Length: 401
• Species: Homo sapiens
• Sequence 2: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 316
• Identity: 158/316 - (50%)
• Similarity: 221/316 - (69%)
• Gaps: 9/316 - (2%)

Human    81 AAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYL 145
            :|.||.|..|||:||:| ||:...:.:||.||:.:|...||||:|.:.|:.. ..|:::..|||:
  Fly    54 SADDTLTNQRVAIKKIS-PFEHQTYCQRTLREITILTRFKHENIIDIRDILR-VDSIDQMRDVYI 116

Human   146 VTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDF 210
            |..||..||..::|.|:|::||:.:.:|||||||||||||:::|||||||||.:|:.|:|||.||
  Fly   117 VQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDF 181

Human   211 GLARHTDDE------MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDH 269
            ||||..|.|      :|.|||||||||||||||...|.:::||||||||:||:|:.|.:|||..:
  Fly   182 GLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHY 246

Human   270 IDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDS 334
            :|||..||.::|:|..:.|:.|.:|.||||::||...|.:.:|.:|..|:.||:|||.|||..:.
  Fly   247 LDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKPNVPWAKLFPNADALALDLLGKMLTFNP 311

Human   335 DKRITAAQALAHAYFAQYHDPDDEPVAD-PYDQSFESRDLLIDEWKSLTYDEVISF 389
            .|||...:||||.|..||:||.|||||: |:..:.|:.|:..|..|||.::|.:.|
  Fly   312 HKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMENDDISRDALKSLIFEETLKF 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK14	XP_011512612.2	None
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	157/313 (50%)
		S_TKc	38..326	CDD:214567	139/273 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810