back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Frk and wnd

DIOPT Version :9

Sequence 1:	NP_001153016.1	Gene:	Frk / 14302	MGIID:	103265	Length:	512	Species:	Mus musculus
Sequence 2:	NP_649137.3	Gene:	wnd / 40143	FlyBaseID:	FBgn0036896	Length:	977	Species:	Drosophila melanogaster

Alignment Length:	312	Identity:	103/312 - (33%)
Similarity:	161/312 - (51%)	Gaps:	37/312 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse   213 KPCLKIQVPT-PFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSM 276
            ||.|.....| ..::..:.::.|:|...||..|:.||||..|.|:.|...|.| ||||.:|.
  Fly   132 KPVLSFIGKTGVIEVKSQRSEDWQIPFESITELEWLGSGAQGAVFSGRLKNET-VAVKKVKE--- 192

Mouse   277 DPNDFLREAQI--MKSLRHPKLIQLYAVCTLEDPIY-IITELMRHGSLQEYLQNDGGSKIHLIQQ 338
                 |:|..|  ::.|.|..:|:...||| :.|:: ||.|...:|.||..|:.:   ::.|..:
  Fly   193 -----LKETDIKHLRKLDHENIIKFKGVCT-QSPVFCIIMEFCPYGPLQNILKEE---QVMLPSR 248

Mouse   339 -VDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESKHEIKL 402
             |..:.|:|.||.||.|...|||||.:.|:|:..:.:.|::|||.:|.:   ||  ..:|.....
  Fly   249 LVSWSKQIALGMQYLHSHKIIHRDLKSPNILISTNEVVKISDFGTSREW---NE--ISTKMSFAG 308

Mouse   403 PVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLSQN-YRLPQPSNCP 466
            .|.|.|||.||....|.|.|:||:|::|:|::|. ::||..:..:.:|..:..| .:|..||.||
  Fly   309 TVAWMAPEVIRNEPCSEKVDIWSYGVVLWEMLTC-EIPYKDVDSSAIIWGVGNNSLKLLVPSTCP 372

Mouse   467 QQFYSIMLECWNVEPKQRPTF------------ETLHWKLEDYFETDCSYSD 506
            :.|..::..||..:|:.||:|            |.|....:.||||..|:.:
  Fly   373 EGFKLLVKLCWKSKPRNRPSFRQILSHLDIAGPELLRKTEKQYFETQKSWKE 424

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.