Protein Alignment DUSP19 and MKP-4

DIOPT Version :10

• Sequence 1: NP_543152.1
• Gene: DUSP19 / 142679
• HGNCID: 18894
• Length: 217
• Species: Homo sapiens
• Sequence 2: NP_608332.2
• Gene: MKP-4 / 32963
• FlyBaseID: FBgn0031044
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 181
• Identity: 62/181 - (34%)
• Similarity: 91/181 - (50%)
• Gaps: 20/181 - (11%)

Human    48 PSSGGGCGYVQDL---------SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNV----- 98
            |||..|.|..||.         ...:.:..:...|.||:..||..::||:..|:||||.:
  Fly    12 PSSSAGGGKAQDSGVLTREDFDGGPVSIDEVDTGLFLGNLTAATHMETLRSFKITHILTLDSVPL 76

Human    99 -AYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVI 162
             .:.:|.:||   |.|.|.|.|:|..:||.:...|.:||..|..:.|.|||||..||||:::.||
  Fly    77 PQHILEASFL---TTKYIQIADMPREDILQHLEGCVDFISSALAQQGNVLVHCYFGVSRSSSTVI 138

Human   163 GFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQE--GKESNKCDR 211
            .::|......|..|:.|||..|..:.||:||:.||:.::.  .|....|.|
  Fly   139 AYMMKRHNLDFLPAYELVKAKRRFVQPNAGFVSQLKLFRRMGCKIDPNCQR 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DUSP19	NP_543152.1	DSP_DUSP19	65..201	CDD:350373	52/141 (37%)
MKP-4	NP_608332.2	DSP	39..175	CDD:350348	52/138 (38%)