DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Flt4 and drpr

DIOPT Version :9

Sequence 1:	NP_032055.1	Gene:	Flt4 / 14257	MGIID:	95561	Length:	1363	Species:	Mus musculus
Sequence 2:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster

Alignment Length:	290	Identity:	63/290 - (21%)
Similarity:	90/290 - (31%)	Gaps:	98/290 - (33%)

- Green bases have known domain annotations that are detailed below.

Mouse   427 KEASSPSIYSRHSRQTLTCTAYGV----PQPLSVQWHWRPWTPCKTFAQRSLRRRQQRDGMPQCR 487
            |:...|:|..|..       .|.|    .:..|.|.....|  |.||.             |:|.
  Fly    21 KDLDGPNICKRRE-------LYNVDVVYTELQSFQERGSTW--CVTFP-------------PRCS 63

Mouse   488 DWKEVTTQDAVNPIESLDSWTEFVEGKNKTVSKLVIQ----DANVSAMYKCVV-VNKVGQDERLI 547
            .::  .....||              |.||::|..|.    |..:::..:||. .::..|..|.|
  Fly    64 TYR--IKHRVVN--------------KTKTIAKNRIVRDCCDGYIASAGECVPHCSEPCQHGRCI 112

Mouse   548 YFYVTTIPDGFSIESEPSEDPLEGQSVRLSCRADNYTYEHLRWYRLNLSTLHDAQGNPLLLDCKN 612
                       |.|....:....|.:..::|...        ||..|.|         :..||.|
  Fly   113 -----------SPEKCKCDHGYGGPACDINCPPG--------WYGRNCS---------MQCDCLN 149

Mouse   613 VHLFATPLEANLEEAE--PGARHATLSLNIPRVAPEDEGDYVCEVQDRRSQDKHCHKKYLSVQAL 675
             :....|...:.|.|:  .|||.|.       :.||......|..:.|......||  ::|.:..
  Fly   150 -NAVCEPFSGDCECAKGYTGARCAD-------ICPEGFFGANCSEKCRCENGGKCH--HVSGECQ 204

Mouse   676 EAPRLTQNLTDLLVNVSDSLEMRCPVAGAH 705
            .||..|..|.|          |||| .|.|
  Fly   205 CAPGFTGPLCD----------MRCP-DGKH 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Flt4	NP_032055.1	IG_like	238..327	CDD:214653
		Ig1_VEGFR	245..329	CDD:143270
		IG_like	341..415	CDD:214653
		Ig	352..418	CDD:299845
		Ig	569..662	CDD:299845	20/94 (21%)
		IG	570..663	CDD:214652	20/94 (21%)
		I-set	678..765	CDD:254352	10/28 (36%)
		IGc2	693..755	CDD:197706	6/13 (46%)
		PKc_like	837..1175	CDD:304357
		Pkinase_Tyr	845..1169	CDD:285015
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1288..1330
drpr	NP_001261276.1	EMI	27..92	CDD:284877	20/102 (20%)
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900