DRSC/TRiP Functional Genomics Resources

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Protein Alignment Flt3 and drpr

DIOPT Version :9

Sequence 1:NP_034359.2 Gene:Flt3 / 14255 MGIID:95559 Length:1000 Species:Mus musculus
Sequence 2:NP_001261276.1 Gene:drpr / 38218 FlyBaseID:FBgn0027594 Length:1042 Species:Drosophila melanogaster


Alignment Length:177 Identity:36/177 - (20%)
Similarity:59/177 - (33%) Gaps:59/177 - (33%)


- Green bases have known domain annotations that are detailed below.


Mouse   366 EKFCFSVRFKAYPRIRCTWIFSQASFPCEQRGLEDGYSISK------FCDHKNKPGEYIFYAEND 424
            |:.|.:.:|......:|...|:. |..|:   ..:|..:.|      .|:...:.|   :|.||.
  Fly   519 ERKCDTGKFGHDCAQKCQCDFNN-SLACD---ATNGRCVCKQDWGGVHCETNCRSG---YYGENC 576

Mouse   425 DAQFTKMFTLNIRKKPQVLANASASQAS----CSSDGYPLPSWTWKKCSDKSP------NCTEEI 479
            |            |..:.|.|:|....|    ||:      .||...|::..|      .|.|..
  Fly   577 D------------KVCRCLNNSSCDPDSGNCICSA------GWTGADCAEPCPPGFYGMECKERC 623

Mouse   480 PEGVWNKKANRKVFGQWVSSSTLNMSEAGKGLLVKCCAYNSMGTSCE 526
            ||.:...|:...:.|:.:                  |....:|.:||
  Fly   624 PEILHGNKSCDHITGEIL------------------CRTGYIGLTCE 652

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Flt3NP_034359.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 45..67
ig 256..346 CDD:278476
PKc_like 573..950 CDD:304357
Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of ligand binding. /evidence=ECO:0000250 592..598
Pkinase_Tyr 611..946 CDD:285015
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 968..1000
drprNP_001261276.1 EMI 27..92 CDD:284877
EGF_CA 274..319 CDD:304395
DSL <479..518 CDD:302925
DSL <567..606 CDD:302925 14/59 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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