DRSC/TRiP Functional Genomics Resources

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Protein Alignment Foxl1 and FoxK

DIOPT Version :9

Sequence 1:NP_032050.2 Gene:Foxl1 / 14241 MGIID:1347469 Length:336 Species:Mus musculus
Sequence 2:NP_001261701.1 Gene:FoxK / 39252 FlyBaseID:FBgn0036134 Length:760 Species:Drosophila melanogaster


Alignment Length:274 Identity:88/274 - (32%)
Similarity:123/274 - (44%) Gaps:50/274 - (18%)


- Green bases have known domain annotations that are detailed below.


Mouse    48 QKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYH-DNRQGWQNSIRHNLSLNECFVKVP 111
            :||||||..||..||..||::::||:|||.||:..:|:|. :..:|||||||||||||..|:||.
  Fly   452 EKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVA 516

Mouse   112 REKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPAAGSPEAKRTRVEPPESEVGCDVGSPDLA 176
            |.:..|||||:|.:||.......:.:|::|:::      |.:..|    ||       .|.|..|
  Fly   517 RSQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQR------SSQGFR----PP-------YGMPRSA 564

Mouse   177 TALPTRAPD-RSQSPAVGTARPALLPWPGP--EPRDPDADLTVQGAGAVASGQLQRPAHH---LG 235
            ...|:...: |..||.......:....||.  |.|..|.::......|....|.|:....   |.
  Fly   565 PVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPEIIYNSQNAHQQQQQQQQQQQQQTLS 629

Mouse   236 SPLCPAPSGSPKGSKSKSFSIDSILAVRPTPASGAEAPGIPKPVPGALG---SSLLAASSGLAPP 297
            :......||||....::|    |.:|...|...|:.|.|      |..|   .:|||....    
  Fly   630 NNSNQYSSGSPYYVTNQS----SGVATPQTHVEGSAASG------GGGGGGVGALLALKRN---- 680

Mouse   298 FNASLVFDAHVQGG 311
                     ||.||
  Fly   681 ---------HVMGG 685

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Foxl1NP_032050.2 FH 49..137 CDD:214627 46/88 (52%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 140..214 17/76 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 227..252 6/27 (22%)
FoxKNP_001261701.1 FHA <170..253 CDD:238017
Forkhead 453..540 CDD:278670 46/86 (53%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2114
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.850

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