DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fhl3 and pk

DIOPT Version :9

Sequence 1:	XP_006502829.1	Gene:	Fhl3 / 14201	MGIID:	1341092	Length:	303	Species:	Mus musculus
Sequence 2:	NP_724538.1	Gene:	pk / 45343	FlyBaseID:	FBgn0003090	Length:	1299	Species:	Drosophila melanogaster

Alignment Length:	272	Identity:	75/272 - (27%)
Similarity:	106/272 - (38%)	Gaps:	65/272 - (23%)

- Green bases have known domain annotations that are detailed below.

Mouse    59 QLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNECYCTAFSSQ--------- 114
            ||..||:     |.|:.|           ||.||    :..||       ..||:|
  Fly   576 QLPPHDN-----EVRYCH-----------SLTDE----ERKEL-------RLFSTQRKRDALGRG 613

Mouse   115 ----------CSACGETVMPGSRKL---EYG-GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCV 165
                      |..|.:.:..|...:   ..| ..:||..||.||.|.:.|....:....|..||.
  Fly   614 NVRQLMSARPCDGCDDLISTGDIAVFATRLGPNASWHPACFACSVCRELLVDLIYFHRDGRMYCG 678

Mouse   166 PCYENKFAPRCARCSKTLTQGGVTYRD-QPWHRECLVCTGCKTPLAGQQFTSRDDDPYCVACFGE 229
            ..:.....|||:.|.:.:.....|..: :.||.....|..|...|.||::..|:..|||:.||..
  Fly   679 RHHAETLKPRCSACDEIILADECTEAEGRAWHMNHFACHECDKQLGGQRYIMREGKPYCLHCFDA 743

Mouse   230 LFAPKCSSCKRPITGGSGGGEGAGLGGGKYVSFEDRHWH--HSCFSCARCSTSLVGQGFVPDGDQ 292
            :||..|..|          ||..|:..|: :|.:.:|||  ..||||..|..||:|:.|:|....
  Fly   744 MFAEYCDYC----------GEAIGVDQGQ-MSHDGQHWHATDECFSCNTCRCSLLGRAFLPRRGA 797

Mouse   293 VLCQ-GCSQAGP 303
            :.|. .||:..|
  Fly   798 IYCSIACSKGEP 809

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fhl3	XP_006502829.1	LIM	<19..47	CDD:351770
		LIM1_FHL3	50..108	CDD:188807	13/48 (27%)
		LIM2_FHL3	112..169	CDD:188811	17/79 (22%)
		LIM3_FHL	176..227	CDD:188732	14/51 (27%)
		LIM	235..299	CDD:351770	21/66 (32%)
pk	NP_724538.1	PET_Prickle	523..618	CDD:193602	16/68 (24%)
		LIM1_Prickle	624..682	CDD:188799	15/57 (26%)
		LIM2_Prickle	687..742	CDD:188802	17/54 (31%)
		LIM3_Prickle	747..805	CDD:188804	21/68 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810