DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fgfr4 and drpr

DIOPT Version :9

Sequence 1:	XP_006517162.3	Gene:	Fgfr4 / 14186	MGIID:	95525	Length:	829	Species:	Mus musculus
Sequence 2:	NP_001261276.1	Gene:	drpr / 38218	FlyBaseID:	FBgn0027594	Length:	1042	Species:	Drosophila melanogaster

Alignment Length:	118	Identity:	27/118 - (22%)
Similarity:	47/118 - (39%)	Gaps:	21/118 - (17%)

- Green bases have known domain annotations that are detailed below.

Mouse    48 TEPGLGCRASEPCLAPILEQQEQVLTVALG----QPVRLCCGRTERGRHWYKEGSRLASAGRVRG 108
            |:.|..|.||....:..:.....:||..|.    .|:  ....:.:..|.|.|      .....|
  Fly   886 TDYGDDCNASGRVGSYSINYNHDLLTKNLNADRTNPI--VYNESLKEEHVYDE------IKHKEG 942

Mouse   109 WRGRLEIAS--FLPEDAGRYLCLARGSMTV---VHNLTLLMDDSLTSISNDED 156
            ::..::|.|  ..|||...:|..:|.|.:.   .|.    |:|::.:|:.||:
  Fly   943 YKDPVKIYSKILFPEDEYDHLDYSRPSTSQKPHYHR----MNDAMLNINQDEE 991

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fgfr4	XP_006517162.3	IGc2	77..134	CDD:197706	12/62 (19%)
		Ig	184..268	CDD:386229
		Ig3_FGFR-2	291..378	CDD:143266
		PTKc_FGFR4	481..794	CDD:133230
drpr	NP_001261276.1	EMI	27..92	CDD:284877
		EGF_CA	274..319	CDD:304395
		DSL	<479..518	CDD:302925
		DSL	<567..606	CDD:302925
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900