DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fcgr1 and bdl

DIOPT Version :9

Sequence 1:	NP_034316.1	Gene:	Fcgr1 / 14129	MGIID:	95498	Length:	404	Species:	Mus musculus
Sequence 2:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	421	Identity:	92/421 - (21%)
Similarity:	146/421 - (34%)	Gaps:	116/421 - (27%)

- Green bases have known domain annotations that are detailed below.

Mouse    32 AVITLQPPWVSIFQKENVTLWCEGPHLPGDSSTQWFINGTAVQ---------ISTP--SYSIPEA 85
            ::|.:.|...:|.:.:.....|...| |.:|...|:.:|..:|         ...|  |.||...
  Fly   151 SLIRIPPVNQTIREGQTAFFHCVMKH-PENSQASWYKDGVLLQEVQDLVRRFYMGPDGSLSIDPT 214

Mouse    86 SFQDSGEYRCQIGSSMPSDPVQLQIHNDWLLLQASRRV--------LTEGEPLALRCH------- 135
            ...|.|||.|::.:|    ..:||....:|.:|...:|        |..|:|..|.||
  Fly   215 MMSDLGEYECKVRNS----DGELQTAKAFLNIQYKAKVIYAPPEVFLPYGQPAVLDCHFRANPPL 275

Mouse   136 ---GW-KNKLV---YNV--VFYR-NGKSFQFSSDSEVAILKTNLSHSGIYHCSGTGRHRYTSAGV 190
               .| |:.|:   |||  |||: ||..|         ..|.:.:|:|.|.|:     .|...|.
  Fly   276 KNLRWEKDGLLFDSYNVPGVFYKMNGSLF---------FAKVDENHAGSYTCT-----PYNDLGT 326

Mouse   191 SITVKELFTTPVLRASVSSPFPE-------GSLVTLNCETNLLLQRPGLQLHFSFYVGSK----- 243
            . ....:.:..|||..:.|..|:       |....|.||.   :.|.| ....|...|.|
  Fly   327 D-GPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAELPCEA---IDRDG-NNRPSIIWGRKDGQPL 386

Mouse   244 -ILEYRNTSSEYHIARAEREDAGFYWCEVATEDSSVLKRSPELELQVLGPQSSAP---------- 297
             ...:..:.....|......|.|.|.|. ||.:::.:....||.::.:.|:  ||
  Fly   387 PADRFSLSGGNLTITGLVEGDRGIYECS-ATNEAATITAEAELMIENIAPR--APYNLTANSTET 448

Mouse   298 ------------------VWFHILFYLSVGIMFSLN-TVLYVKIHRLQREKKYNLEVPLVSEQGK 343
                              ||:.::.......:..|: .|:...:..||..|:|..   :|..|.|
  Fly   449 CITIRWQPGYLRPNLEYTVWYRLMEAPEWRTLRVLDKKVMEATVQHLQPGKEYEF---MVLSQDK 510

Mouse   344 KANSFQQVRSDGVYEEVTATASQTTPKEAPD 374
                    ..||::.:.....:..:|..|.|
  Fly   511 --------YGDGMFSKQFRFQTLPSPIRADD 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fcgr1	NP_034316.1	Ig1_FcgammaR_like	32..110	CDD:143229	21/88 (24%)
		IG_like	38..110	CDD:214653	20/82 (24%)
		Ig	114..194	CDD:299845	28/104 (27%)
		IG_like	125..194	CDD:214653	24/85 (28%)
		ig	205..283	CDD:278476	18/90 (20%)
		IG_like	213..271	CDD:214653	14/70 (20%)
		Interaction with EPB41L2. /evidence=ECO:0000250	321..342		5/20 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	346..404		5/29 (17%)
bdl	NP_608822.1	IG_like	42..128	CDD:214653
		Ig	43..131	CDD:299845
		I-set	153..242	CDD:254352	23/93 (25%)
		Ig	157..242	CDD:299845	22/89 (25%)
		Ig_2	252..337	CDD:290606	25/99 (25%)
		IG_like	260..327	CDD:214653	24/80 (30%)
		I-set	341..428	CDD:254352	18/91 (20%)
		IGc2	356..419	CDD:197706	16/67 (24%)
		FN3	435..524	CDD:238020	16/101 (16%)
		FN3	554..636	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000