| Sequence 1: | NP_034311.2 | Gene: | Fbn2 / 14119 | MGIID: | 95490 | Length: | 2907 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001137905.1 | Gene: | frac / 38850 | FlyBaseID: | FBgn0035798 | Length: | 1618 | Species: | Drosophila melanogaster |
| Alignment Length: | 1456 | Identity: | 381/1456 - (26%) |
|---|---|---|---|
| Similarity: | 520/1456 - (35%) | Gaps: | 556/1456 - (38%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 1062 PFYKDINECKAFPGMCTYGKCRNTI------GSFKCRCNNGFALDMEE-RNCTDIDECRISPDLC 1119
Mouse 1120 GSGICVNTPGSFECECFEGY---ESGFMMMKNCMDIDECERNPLL---CRGGTCVNTEGSFQCDC 1178
Mouse 1179 PLGHELSPSREDCVD-----INECSLSDNLCRN---GKCVNMIGTYQCSCNPGYQATPDRQGCTD 1235
Mouse 1236 IDECMI-------MNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECEN--NPDI----C 1287
Mouse 1288 DGGQCTNIP-GEYRCLCYDGFMASMDMKTCIDVNECDLNPNICMFGECENTKGSFICHCQLGYSV 1351
Mouse 1352 KKGTTGCTDVDECEIGAHNCDMHASCL----NVPGSFKCSCREGWVGNGIKCIDLDECANGTHQC 1412
Mouse 1413 SINAQCVNTPGSYRCACSEGFT-GDGFTCSDVDECAENTNLCENGQCLNVPGAYRCECEMGFTPA 1476
Mouse 1477 SDSRSCQDIDECSFQNICVFGTCNNLPGMFHCICDDGYE---LDRTGGNCTDIDECADPINCVNG 1538
Mouse 1539 LCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEVGVGVSRSSCCCSL 1603
Mouse 1604 GKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQC 1668
Mouse 1669 ECPQGYYLSEETRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFC 1733
Mouse 1734 YRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGK 1798
Mouse 1799 AVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINS 1863
Mouse 1864 PGSYRCECAAGFKLSPNG-ACVDRNECLEIPNVCSHGLCVDLQGSYQCICNNGFKASQDQTMCMD 1927
Mouse 1928 VDECERHPCG--NGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECS-SFFGQVCRNGRCFNEIGS 1989
Mouse 1990 FKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVRSE--NCIDINE 2052
Mouse 2053 CDEDPNICLFGSCTNTPGGFQCICPPGFVLSDNGRRCFDTRQSF--------------CFTNF-- 2101
Mouse 2102 ---ENGK------------CSVPK-----------AFNTTKAKC-CCSKMPGEGWGD---PCELC 2136
Mouse 2137 PKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTG 2201
Mouse 2202 VRCVDTDECSIGNPCGNGTCTNVIGSFECTCNEGFEPGPMMNCEDINE-CAQNPLLCAFRCMNTF 2265
Mouse 2266 GSYECTCPVGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCV 2330
Mouse 2331 DENECRTKPG----ICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTMCQMA 2391
Mouse 2392 SSSRNLVTKSECCCDGGRGWGHQCEL 2417 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Fbn2 | NP_034311.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 26..58 | ||
| Interaction with MFAP4. /evidence=ECO:0000250|UniProtKB:P35556 | 149..359 | ||||
| TB | 225..258 | CDD:279073 | |||
| EGF_CA | 276..>306 | CDD:214542 | |||
| TB | 375..412 | CDD:279073 | |||
| EGF_CA | 528..558 | CDD:214542 | |||
| EGF_CA | 568..609 | CDD:214542 | |||
| EGF_CA | 610..642 | CDD:238011 | |||
| cEGF | 631..654 | CDD:289433 | |||
| EGF_CA | 651..691 | CDD:214542 | |||
| TB | 708..744 | CDD:279073 | |||
| cEGF | 783..806 | CDD:289433 | |||
| EGF_CA | 803..838 | CDD:238011 | |||
| TB | 900..>928 | CDD:279073 | |||
| TB | 1005..1040 | CDD:279073 | |||
| EGF_CA | 1108..1142 | CDD:214542 | 19/36 (53%) | ||
| EGF_CA | 1151..1183 | CDD:214542 | 16/34 (47%) | ||
| EGF_CA | 1193..1225 | CDD:214542 | 8/39 (21%) | ||
| cEGF | 1216..1238 | CDD:289433 | 8/21 (38%) | ||
| FXa_inhibition | 1239..1274 | CDD:291342 | 15/41 (37%) | ||
| Plasmod_Pvs28 | 1286..1439 | CDD:283826 | 48/162 (30%) | ||
| EGF_3 | 1364..1399 | CDD:289699 | 10/38 (26%) | ||
| EGF_3 | 1405..1440 | CDD:289699 | 16/35 (46%) | ||
| EGF_CA | 1484..1519 | CDD:214542 | 18/37 (49%) | ||
| EGF_CA | 1525..1556 | CDD:214542 | 5/30 (17%) | ||
| TB | 1586..1621 | CDD:279073 | 0/34 (0%) | ||
| EGF_CA | 1643..1675 | CDD:214542 | 0/31 (0%) | ||
| cEGF | 1665..1688 | CDD:289433 | 2/22 (9%) | ||
| Interaction with MFAP4. /evidence=ECO:0000250|UniProtKB:P35556 | 1728..2164 | 145/487 (30%) | |||
| TB | 1742..1779 | CDD:279073 | 3/36 (8%) | ||
| EGF_CA | 1801..1833 | CDD:214542 | 15/31 (48%) | ||
| vWFA | <1840..1881 | CDD:294047 | 17/40 (43%) | ||
| vWFA | <1880..1922 | CDD:294047 | 13/42 (31%) | ||
| EGF_CA | 1927..1961 | CDD:214542 | 13/35 (37%) | ||
| EGF_CA | 1966..2008 | CDD:214542 | 14/42 (33%) | ||
| EGF_CA | 2049..2089 | CDD:214542 | 17/39 (44%) | ||
| TB | 2106..2143 | CDD:279073 | 12/51 (24%) | ||
| EGF_CA | 2164..2205 | CDD:214542 | 7/40 (18%) | ||
| EGF_CA | 2206..2245 | CDD:214542 | 4/38 (11%) | ||
| vWFA | <2244..2283 | CDD:294047 | 6/39 (15%) | ||
| TB | 2390..2425 | CDD:279073 | 4/28 (14%) | ||
| vWFA | <2482..2522 | CDD:294047 | |||
| vWFA | <2520..2556 | CDD:294047 | |||
| EGF_CA | 2607..>2636 | CDD:214542 | |||
| Cadherin_repeat | <2821..>2868 | CDD:206637 | |||
| frac | NP_001137905.1 | FXa_inhibition | 296..331 | CDD:291342 | 18/39 (46%) |
| cEGF | 396..415 | CDD:289433 | 8/18 (44%) | ||
| FXa_inhibition | 425..458 | CDD:291342 | 14/32 (44%) | ||
| FXa_inhibition | 476..505 | CDD:291342 | 11/29 (38%) | ||
| vWFA | <550..586 | CDD:294047 | 20/37 (54%) | ||
| FXa_inhibition | 596..630 | CDD:291342 | 13/35 (37%) | ||
| FXa_inhibition | 636..>664 | CDD:291342 | 12/27 (44%) | ||
| EGF_CA | 676..715 | CDD:284955 | 18/197 (9%) | ||
| FXa_inhibition | 745..780 | CDD:291342 | 11/35 (31%) | ||
| FXa_inhibition | 786..821 | CDD:291342 | 13/36 (36%) | ||
| FXa_inhibition | 827..862 | CDD:291342 | 10/35 (29%) | ||
| FXa_inhibition | 874..904 | CDD:291342 | 11/34 (32%) | ||
| FXa_inhibition | 945..980 | CDD:291342 | 18/35 (51%) | ||
| CCP | 1110..1170 | CDD:153056 | 15/108 (14%) | ||
| CCP | 1183..1235 | CDD:153056 | 20/99 (20%) | ||
| DUF5011 | 1468..1536 | CDD:295940 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E33208_3BA2W | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D4721at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 1 | 1.000 | - | - | otm42398 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100900 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X1431 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 6 | 5.720 | |||||