Protein Alignment CRYAB and cryaba

DIOPT Version :10

• Sequence 1: NP_001876.1
• Gene: CRYAB / 1410
• HGNCID: 2389
• Length: 175
• Species: Homo sapiens
• Sequence 2: NP_571232.1
• Gene: cryaba / 30393
• ZFINID: ZDB-GENE-991119-2
• Length: 168
• Species: Danio rerio
• Alignment Length: 168
• Identity: 105/168 - (62%)
• Similarity: 128/168 - (76%)
• Gaps: 5/168 - (2%)

Human     1 MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFL-RAPSWFDTG 64
            |:|:|.|||.|||.||...|.|:|||:|||||.:||  |.|...:.||.||  :| |.|||:|:|
Zfish     1 MEISIQHPWYRRPLFPGFFPYRIFDQYFGEHLSDSD--PFSPFYTMFYYRP--YLWRFPSWWDSG 61

Human    65 LSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVD 129
            :||||.::|||.:|||||||||:||.|||..|.||:||||:||||:||.::|||.|||:|||.||
Zfish    62 MSEMRQDRDRFVINLDVKHFSPDELTVKVNEDFIEIHGKHDERQDDHGIVAREFFRKYKIPAGVD 126

Human   130 PLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKP 167
            |..||||||||||||:|..|.|:...||:|||...|||
Zfish   127 PGAITSSLSSDGVLTINTLRHQLDILERSIPIICGEKP 164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRYAB	NP_001876.1	Crystallin	1..55	CDD:425732	29/53 (55%)
		ACD_alphaB-crystallin_HspB5	67..150	CDD:107246	58/82 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..175		11/22 (50%)
cryaba	NP_571232.1	Crystallin	1..53	CDD:425732	30/55 (55%)
		alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.	64..143	CDD:469641	57/78 (73%)