Protein Alignment CRYAA and CG4461

DIOPT Version :10

• Sequence 1: NP_000385.1
• Gene: CRYAA / 1409
• HGNCID: 2388
• Length: 173
• Species: Homo sapiens
• Sequence 2: NP_648304.1
• Gene: CG4461 / 39074
• FlyBaseID: FBgn0035982
• Length: 200
• Species: Drosophila melanogaster
• Alignment Length: 177
• Identity: 52/177 - (29%)
• Similarity: 76/177 - (42%)
• Gaps: 18/177 - (10%)

Human     5 IQHPWFKRTLGPFY--PSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTV----------- 56
            :.||.:...|.|:.  .|||:  :........|||..|...:|...|..|.::.
  Fly    21 LYHPPYDFQLYPYLWDDSRLW--WPSPHTSRSDLLRPLDELVSRRVRNQLIQSTPYEWAHPMRWD 83

Human    57 -LDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQD-DHGYISREFHRRYR 119
             ..|| ..|..|...|.|.:||:.|.|.|:.||..||:|.:.|.||.|.: .:|.:.|.|.|:|.
  Fly    84 NYYSG-ERVHVDEKGFRIDIDVRQFHPHDIVVKTNDDYVIVQGNHNRRDEGSNGLVERHFVRKYL 147

Human   120 LPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEK 166
            ||...:.:.:...:|:||:||...|........|..||.:.|....|
  Fly   148 LPRGYNANEVISDISSDGILTIKAPPPPPAKYYTPGERLVRVHETGK 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRYAA	NP_000385.1	Crystallin	1..54	CDD:425732	14/50 (28%)
		ACD_alphaA-crystallin_HspB4	60..145	CDD:107245	31/85 (36%)
CG4461	NP_648304.1	metazoan_ACD	94..169	CDD:107247	28/74 (38%)