Protein Alignment CNBD2 and pnpla6

DIOPT Version :10

• Sequence 1: XP_047295877.1
• Gene: CNBD2 / 140894
• HGNCID: 16145
• Length: 635
• Species: Homo sapiens
• Sequence 2: XP_005160109.1
• Gene: pnpla6 / 560986
• ZFINID: ZDB-GENE-050107-4
• Length: 1343
• Species: Danio rerio
• Alignment Length: 457
• Identity: 88/457 - (19%)
• Similarity: 153/457 - (33%)
• Gaps: 138/457 - (30%)

Human    31 EEESEEEPECLEIDFKSRTLSVRRFGLQIEKPRCQKMKDWSKIRKLGLYQLAMDIIIMIRVCKMF 95
            :.||.|.||            ..||| .| |...:.....|.:  :|:...|..:|::|.|...|
Zfish     7 DTESAEPPE------------TDRFG-NI-KSLVEDQLQTSMV--VGIVIGAGVVIVLIAVLIFF 55

Human    96 ---RQGLRGFREYQIIETAHWKHPIFSFWDKKMQSRVTFDTMDFIAEEGHFPPK----------- 146
               |..||.....::.:....|.....|:.:|:..:|:..|...:.......|:
Zfish    56 VLRRMQLRKLEAQEVPKYRFRKRDKVLFYGRKIMRKVSQSTSSLVGATSSTRPRLKKKQKMLNIA 120

Human   147 -----------AIQIMQKKPSWRTEDEIQ-AVCN------ILQVLDSYR---NYAEPLQLLLAKV 190
                       .:|:.:..||....|..: .|.|      :|.:|.:.|   ::.:||.|.|.|.
Zfish   121 KKILRFKKEVPTLQMKEPPPSVLEADLTEFDVANSHLPSEVLYMLKNVRVLGHFEKPLFLELCKH 185

Human   191 MRFERFGRRRVIIKKGQKGNSFYFIYLGTVAI-TKDEDGSSAFLDPHPKLLHKG----SCFGEMD 250
            |.|.:|.:...:.:.||..:|.|.:..|.:.: ...:||....:    |.::.|    |....:|
Zfish   186 MVFLQFQQGEYVFRPGQPDSSIYVVQDGKLELCLTGQDGKDGVV----KEVYPGDSVHSLLSILD 246

Human   251 VLHASVRRSTIVCMEETEFLVVDR--EDFFANKLDQEVQKDAQYRFEFFRKMELFASWSDE--KL 311
            |:....|....|.....|...|.|  .|.|                     :.:|..:.:.  ::
Zfish   247 VITGHQRPYKTVSARAAEVSTVLRLPVDAF---------------------LSIFEKYPESLVRV 290

Human   312 WQLVAMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLD-LGASPSYRRWIWQHLELIDGR 375
            .|:: |.:::|.:                        ||.|.: ||.:..    ::.|.......
Zfish   291 VQII-MVRLQRVT------------------------VLALHNYLGLTNE----LFSHEMQPRSS 326

Human   376 PLKTHLSEYSPMERFKEFQIKSYPLQDFSSLKLPHLKKAWGLQGTSFSRKIRTSGD------TLP 434
            ||..|.:..||:...|.          |.||.:|...:...:|..       |.||      |:|
Zfish   327 PLSPHPTRSSPVRHSKR----------FGSLTVPDKHREAAVQNA-------TGGDHGKEGGTIP 374

Human   435 KM 436
            .:
Zfish   375 TL 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNBD2	XP_047295877.1	CAP_ED	181..277	CDD:237999	25/102 (25%)
pnpla6	XP_005160109.1	TM_EGFR-like	31..64	CDD:213052	9/34 (26%)
		CAP_ED	170..291	CDD:237999	28/145 (19%)
		CAP_ED	467..577	CDD:237999
		CAP_ED	590..698	CDD:237999
		Pat_PNPLA6_PNPLA7	921..1226	CDD:132864