Protein Alignment CNBD2 and pnpla7b

DIOPT Version :9

• Sequence 1: XP_011526892.1
• Gene: CNBD2 / 140894
• HGNCID: 16145
• Length: 617
• Species: Homo sapiens
• Sequence 2: XP_692276.5
• Gene: pnpla7b / 503936
• ZFINID: ZDB-GENE-050309-66
• Length: 1340
• Species: Danio rerio
• Alignment Length: 593
• Identity: 115/593 - (19%)
• Similarity: 192/593 - (32%)
• Gaps: 190/593 - (32%)

Human    90 IETAHWKHPIFSFWDKKMQSRVTFDTMDFIAEEGHFPPKAIQIMQKKPSWRTEDEIQAVCN---- 150
            :|:.|...|     |..|       |.|..::|....|.|||...:|.|........||.:
Zfish   398 LESTHAGSP-----DHNM-------TFDRSSKEAPSSPIAIQKSNRKKSVTMHHSPSAVFHYSDT 450

Human   151 --------------ILQVLDSYRNYAEPLQL----LLAKVMRFERFGRRRVIIKKGQKGNSFYFI 197
                          |.|.  :.|:..:.:||    ||...:...:.....|:..:|.:..|..|:
Zfish   451 GGHSSHIHHSKVNAIFQA--AKRDLLKIIQLQDPNLLEDRVTLRQVKAGSVVASEGDQDVSVQFV 513

Human   198 YLGTVAITK---DEDGSSAFLDPHPKLLHKGSCFGEMDVLHA-----SVRRSTIVCMEETEFLVV 254
            ..||:.:.:   |.:..|.....||     |...|.:.||..     |||.....|     ||.:
Zfish   514 ISGTLHVYQRLIDREEQSCLFVAHP-----GEMVGHLAVLTGEPLIFSVRAQRDCC-----FLSI 568

Human   255 DREDFFANKLDQEVQKDAQYRF-------------EFFRKMELFASWSDEKLWQLVAMA-KIERF 305
            .:..|:      |:.: |:.|.             .|.|:::....|          || :..|.
Zfish   569 SKTHFY------EIMR-AEPRMVLNVAHTVVRRVSSFVRQIDFALDW----------MALEAGRA 616

Human   306 SYGQLISKDFGESPFIMFISKGSCEVLRLLDLG---ASPSYRRWIWQHLELIDGRPLKTHLSEYS 367
            .|.|   .|..:|.||  :..|....:.:.|.|   .:..|.|.     :||......|||:..:
Zfish   617 VYRQ---GDKSDSTFI--VLSGRLRSVIMKDDGKKELAGEYGRG-----DLIGVVEALTHLNRAT 671

Human   368 PMERFKEFQIKSYPLQDFSSLK---------LPHL--KKAWG-LQGTSFSRKIRTSGDTLPKMLG 420
            .:...::.::...|....:|:|         |.||  :|..| :|..:....:|:.|...|....
Zfish   672 TVHAVRDSELAKLPEGALNSIKRKYPQVVTRLIHLLGQKILGNMQQVNGPLSVRSLGFHSPTSKW 736

Human   421 PKIQSRPAQSIKCAMINIKPGELPKEA---------------------------AVGAYVKVHTV 458
            .  ...||.::....|.....|:|..|                           .|.|...||..
Zfish   737 D--AGNPAANLSTVTILPVSEEVPLTAFTLELQHALSAIGPTLLLTSDIIRQRLGVAALDSVHEY 799

Human   459 EQGEILG----LHQAFLPEGECDTRP-----------LILMSLGNE--------------LIRIR 494
            .....||    :|:..|.:.:....|           :|::.||.:              .:|.:
Zfish   800 RLSSWLGQQEDIHRIVLYQSDGSLTPWTQRCIRQADCIIIVGLGEQEPTVGELERMLESSAVRAQ 864

Human   495 KEIFYELIDNDDEMIKKLLKLNIAFPSDEDMCQKFLQQNSWNIFRKDLLQLLVEPCQSQLFT-PN 558
            |::.  |:..:|.            |......: :|...||      :.:.|...|..::|: .:
Zfish   865 KQLV--LLHREDG------------PPPAGTVE-WLNMRSW------ISRHLHLSCPHRVFSRRS 908

Human   559 RPKKREIY 566
            .||.||:|
Zfish   909 LPKLREMY 916

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNBD2	XP_011526892.1	Crp	151..>282	CDD:223736	33/155 (21%)
		CAP_ED	163..259	CDD:237999	24/107 (22%)
pnpla7b	XP_692276.5	Crp	164..354	CDD:223736
		CAP_ED	170..291	CDD:237999
		Crp	470..>602	CDD:223736	31/148 (21%)
		CAP_ED	473..583	CDD:237999	27/126 (21%)
		Crp	596..>718	CDD:223736	31/141 (22%)
		CAP_ED	596..704	CDD:237999	25/127 (20%)
		Pat_PNPLA6_PNPLA7	927..1232	CDD:132864
		RssA	932..1234	CDD:224666

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810