Protein Alignment CNBD2 and M110.7

DIOPT Version :9

• Sequence 1: XP_011526892.1
• Gene: CNBD2 / 140894
• HGNCID: 16145
• Length: 617
• Species: Homo sapiens
• Sequence 2: NP_495734.3
• Gene: M110.7 / 187474
• WormBaseID: WBGene00010915
• Length: 1095
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 114/620 - (18%)
• Similarity: 206/620 - (33%)
• Gaps: 198/620 - (31%)

Human    36 EEPECLEIDFKSRTLSVRRFGLQGLYQLAMDIIIMI-----------------RVC--KMFRQGL 81
            ::.|.|.||..|..||..|         |.|:|:::                 ..|  |..|.|.
 Worm   142 KDVETLSIDTGSVVLSPGR---------ANDVIVVVISGELGIFTNVSLGDKRYDCNIKTLRSGE 197

Human    82 RGFREYQIIET----------AHWK---------HPIFSF----------WDKKMQ------SRV 111
            ..|.:..|||.          .|.|         :.:.||          |.:.:|      .:.
 Worm   198 SYFSQTSIIEILMNEKPNNKYIHLKALTSCRVATYHLTSFHTSFIANPQQWIRTIQVVMTRLQQC 262

Human   112 TFDTMDFIAEEGHFPPKAIQIMQKKP--------SWRTEDE-----IQAVCNILQVLDSYRNYAE 163
            |..|.:.....|   .|.:...:|.|        :..||.|     ::|:...:.:.|......|
 Worm   263 TLITCNMYLGIG---GKCLNAKRKLPDSGKFKDFNKLTEAEQLNKGVEAIAQAMGIPDQSDKLRE 324

Human   164 PLQLLLAKVMRFE-RFGRRRVIIKKGQKGNSF----YFIYLGTVAITK-----DEDGSSAFLDPH 218
                   ||.::| :.|  .|:.::    |||    .|:..|.:.:.:     |:.|:|...|.:
 Worm   325 -------KVRKYECQAG--TVVTEE----NSFEIDMIFVVFGKLRLKRGDLEHDDTGTSLTFDVY 376

Human   219 PKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF----FANKLD--QEVQKDAQYRFE 277
            |     |.....|.:|.......:...:|:|.:..:.|:::    ||:.:.  :......|:...
 Worm   377 P-----GDMLPSMQILTNEPAMCSAKALEKTIYFKICRDEYIQFLFAHPVIYLRLAFHALQFISP 436

Human   278 FFRKMELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLD-LGASP 341
            |.|..::...|              .|...||.:.:...:|..:..:..|.   ||.:| .....
 Worm   437 FARVFDMAVHW--------------HRIETGQALFRQGDKSDSMHIVMGGR---LRAVDSTKIIE 484

Human   342 SYRRWIWQHLELIDGRPLKTHLSEYSPME------RFKEFQIKSYPLQDFSSLKLPH-------- 392
            .|.|     |:||.    .|.::|..|..      ||.........|..|..::.|.
 Worm   485 EYGR-----LDLIG----ITDMAEKRPRRNTVMAVRFSHIVCIPENLLSFVKIRYPQVGNKLLKL 540

Human   393 LKKAWGLQ--------GTSFSRKIRTSGDTLPKMLGPKIQSRPAQSIKCAMIN-----IKPGELP 444
            :.|.|...        .|:.::.:||..      :.|..:..|.....|.:.|     :|...|
 Worm   541 ISKCWKAPTPETMSHVETTRNQNLRTIA------IVPASRRVPLTEFTCELYNQLSKHVKTLRL- 598

Human   445 KEAAVGAYVKVHTVEQGEILGL-HQAFLPE-------GECD------TR-------PLILMSLGN 488
            ..:.|..|.:...:.:....|| |...:.|       .:||      ||       .:::::||.
 Worm   599 SSSVVENYFESEVITKKADYGLMHWLNVQEIAYSLVLYQCDFHKTNWTRRCLRMADAILMVALGT 663

Human   489 ELIRIRKEIFYE-LIDNDDEMIKKLLKLNIAFPSD 522
            |  ...:::..| |:..:::.:::..:|...:|.|
 Worm   664 E--SKEEQVLAEALLSCNEKGVRQSKELVFLWPID 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNBD2	XP_011526892.1	Crp	151..>282	CDD:223736	28/146 (19%)
		CAP_ED	163..259	CDD:237999	22/105 (21%)
M110.7	NP_495734.3	CAP_ED	316..427	CDD:237999	25/128 (20%)
		Crp	325..>432	CDD:223736	23/117 (20%)
		Crp	423..>543	CDD:223736	25/145 (17%)
		CAP_ED	444..538	CDD:237999	22/119 (18%)
		Patatin_and_cPLA2	752..1040	CDD:299702
		RssA	756..1046	CDD:224666

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900