Protein Alignment NANP and Reg-2

DIOPT Version :10

• Sequence 1: NP_689880.1
• Gene: NANP / 140838
• HGNCID: 16140
• Length: 248
• Species: Homo sapiens
• Sequence 2: NP_612043.1
• Gene: Reg-2 / 38075
• FlyBaseID: FBgn0016715
• Length: 260
• Species: Drosophila melanogaster
• Alignment Length: 227
• Identity: 54/227 - (23%)
• Similarity: 88/227 - (38%)
• Gaps: 58/227 - (25%)

Human     3 LSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQV-KLSKECFHPYNT 66
            |||.|.:.||:.|||:.......:...|:..|..::          ||..:: |..|..::..|.
  Fly     4 LSRFRLITFDVTNTLLQFRTTPGKQYGEIGALFGAR----------CDNNELAKNFKANWYKMNR 58

Human    67 CITDL-RTSH--------WEEAIQET--KGGAA--NRKLAE------ECY---FLWKSTRLQHMT 109
            ...:. |.::        |.:.|..|  :.|||  :.||..      |.|   ..|:.
  Fly    59 DYPNFGRDTNPQMEWQQWWRKLIAGTFAESGAAIPDEKLHNFSNHLIELYKTSICWQP------- 116

Human   110 LAEDVKAMLTELRKEV-----RLLLLTNGDRQ----TQREKIEACACQSYFDAVVVGGEQREEKP 165
             ......:|.:||||:     :|.::.|.|.:    .|..|::     .|.|..:...|.:.|||
  Fly   117 -CNGSVELLQQLRKELKPEKCKLGVIANFDPRLPTLLQNTKLD-----QYLDFAINSYEVQAEKP 175

Human   166 APSIFYYC---CNLLGVQPGDCVMVGDTLETD 194
            .|.||...   ..|..::|.:|:.:||...||
  Fly   176 DPQIFQKAMEKSGLKNLKPEECLHIGDGPTTD 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NANP	NP_689880.1	CTE7	6..234	CDD:274057	51/224 (23%)
Reg-2	NP_612043.1	DREG-2	8..220	CDD:274056	51/223 (23%)