Protein Alignment ptprsa and Ptp36E

DIOPT Version :10

• Sequence 1: XP_068072483.1
• Gene: ptprsa / 140820
• ZFINID: ZDB-GENE-020107-3
• Length: 1936
• Species: Danio rerio
• Sequence 2: NP_609872.1
• Gene: Ptp36E / 35091
• FlyBaseID: FBgn0267486
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 589
• Identity: 188/589 - (31%)
• Similarity: 303/589 - (51%)
• Gaps: 57/589 - (9%)

Zfish  1384 EYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILAPIEGITGSDYINSNYIDGYRKQNA 1448
            |:::....:..|..|:..:.|..||:....|.||::||:|..:.|:..|||:|::|:|...|.||
  Fly   105 EFQTAAKVESNTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDSLLKPNA 169

Zfish  1449 YIATQGPLPETFGDFWRMVWEQRAATVVMMTRLEEKSRIKCDQYWPSRGT--ETYGMIQVTLLDT 1511
            ||.||||:.||...:|||||::..:.:||:|:..:.:::.|.||||....  |.||.|.:.::..
  Fly   170 YIVTQGPVEETVQAYWRMVWQENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVRE 234

Zfish  1512 IELATFCVRTFSLHKNGSSEKREVR------QFQFTAWPDHGVPEYPTPFLAFLRRVKTC----- 1565
            .:||.|.:|||.|:|  .:||:||.      ||.:|.|..|..| :....|.|.|||:..
  Fly   235 EQLANFHIRTFRLYK--MNEKQEVTDERLILQFHYTEWYSHSCP-FSNALLEFRRRVRLVVGNII 296

Zfish  1566 -NPPD-AGPIIAHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSF 1628
             :..| .|||:.|||.|.||:|.::.|||.||..:.|:..:::|::..:|..|..:|:..:||.|
  Fly   297 KDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKF 361

Zfish  1629 IHDALLEAVACGNTEVAARSLFSYIQKLAQVEAGEHVSGMELEFKRLANSKAHTSRFISANLPC- 1692
            |:|.|.|.:.||.|......|...::..|:..:|..::..:.|:.::..   .|.||...:  |
  Fly   362 IYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICK---QTPRFTIGD--CA 421

Zfish  1693 ------NKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINSSFIDGYRQQKAYIATQGPLAETTED 1751
                  |:.|||.|..:|.:..|..|...:|...:|||||.|:|||.:.:.||.|:.|:..|..:
  Fly   422 GGHRADNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGE 486

Zfish  1752 FWRMLWENNSTIVVMLTKLREMGREKCHQYWPAERSARYQY------FVVDPMAEYNMPQYILRE 1810
            ||.::::...:.||:|.:..... ::...:|| .:|...:|      ..|...:..|:.|:   |
  Fly   487 FWSLVYDQECSAVVVLCQPPSQS-QQYPSFWP-NKSKMEKYGPVFSVHYVMSKSYTNIKQW---E 546

Zfish  1811 FKV-------TDARDG---QSRTVRQFQFTDWP-EQGVPKSGEGFIDFIGQVH--KTKEQFGQDG 1862
            ||:       |:...|   .:|||:.||.|.|| ...||.|....:..:..|.  :.|..:   |
  Fly   547 FKINKKIVSLTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVDY---G 608

Zfish  1863 PISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEY 1927
            |:.|....|..|.||:...:..:|::...|.||:||.||.:|..||.:|:...||::||...|.|
  Fly   609 PVCVVSPDGRSRAGVYCAANACIEQVIQHGEVDVFQAVKTVRRHRPQLVENMTEYKYCYDLVLHY 673

Zfish  1928 LGSF 1931
            :..|
  Fly   674 VLHF 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ptprsa	XP_068072483.1	I-set	31..122	CDD:400151
		Ig strand B	48..52	CDD:409353
		Ig strand C	61..65	CDD:409353
		Ig strand E	84..91	CDD:409353
		Ig strand F	102..107	CDD:409353
		Ig strand G	115..118	CDD:409353
		IgI_2_RPTP_IIa_LAR_like	135..224	CDD:409400
		Ig strand A'	141..145	CDD:409400
		Ig strand B	148..157	CDD:409400
		Ig strand C	162..168	CDD:409400
		Ig strand C'	170..172	CDD:409400
		Ig strand D	181..185	CDD:409400
		Ig strand E	188..193	CDD:409400
		Ig strand F	202..209	CDD:409400
		Ig strand G	212..223	CDD:409400
		IgI_3_RPTP_IIa_LAR_like	237..318	CDD:409401
		Ig strand A	237..239	CDD:409401
		Ig strand A'	243..247	CDD:409401
		Ig strand B	250..258	CDD:409401
		Ig strand C	263..269	CDD:409401
		Ig strand C'	271..273	CDD:409401
		Ig strand D	276..280	CDD:409401
		Ig strand E	285..290	CDD:409401
		Ig strand F	297..304	CDD:409401
		FN3	307..837	CDD:442628
		Ig strand G	308..317	CDD:409401
		FN3	792..>1088	CDD:442628
		fn3	922..1006	CDD:394996
		R-PTPc-S-1	1358..1639	CDD:350473	98/269 (36%)
		R-PTP-S-2	1641..1930	CDD:350475	87/314 (28%)
Ptp36E	NP_609872.1	Y_phosphatase	125..368	CDD:459674	94/245 (38%)
		Y_phosphatase	428..671	CDD:459674	76/250 (30%)