Protein Alignment Faah and CG5191

DIOPT Version :9

• Sequence 1: NP_034303.3
• Gene: Faah / 14073
• MGIID: 109609
• Length: 579
• Species: Mus musculus
• Sequence 2: NP_650893.2
• Gene: CG5191 / 42431
• FlyBaseID: FBgn0038803
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 155/639 - (24%)
• Similarity: 238/639 - (37%)
• Gaps: 194/639 - (30%)

Mouse     3 LSEVWTALSGLSGVCLACSLLSAAVVLRWTRSQTARGAVTRARQKQRAGLETMDKAVQRFRLQNP 67
            |.|:|..   :.|..:...|.||.:|..|.       .|..:|.       |..|.::|   :.|
  Fly    13 LEELWLR---ILGYIMRRFLRSAMIVFSWF-------VVPYSRY-------TNIKVIRR---KLP 57

Mouse    68 DLDSEALLALPLLQLVQKLQSGELSPEAVLFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPR-- 130
            .:.|. ||.:|.:.|.:.:::.::..|.|:..|:.:..:||...|.:..  ...|..|.:|..
  Fly    58 PIRSH-LLEIPAVDLAKLIRTRKIKSEEVVEAYIERCRQVNPLINAIVQ--DRFEEALEEAREID 119

Mouse   131 ----QGL-----------LYGVPVSLKECFSYKGHASTLGLSLNEGVTSESDCVVVQVLKLQGAV 180
                .|:           |.|:||::||..:.||..:..|........::||..||:.:|..|.:
  Fly   120 NVIAMGINSVESMEELTPLLGIPVTVKESIAVKGMTNQAGRVFKTPQIAKSDAPVVEQIKRSGGI 184

Mouse   181 PFVHTNVPQSMLSYDCSNPLFGQTMNPWKPSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFP 245
            ..:.:|.|:..|.::..|.:.|||.||:...::||||||||.||:.||.|.|||.:|||||.|.|
  Fly   185 ILLVSNTPELCLLWETYNNVTGQTKNPYDLKRTPGGSSGGEAALLASGASLLGLTSDIGGSSRLP 249

Mouse   246 SAFCGICGLKPTGNRLS-KSGLKSCVYGQTAVQLSVGPMARDVDSLALCMKALLCEDLFRLDSTI 309
            :.|.||.|.|||...:| |....:..:.:.....::.||.|....|.|.:|.:       .|.|.
  Fly   250 AMFSGIWGHKPTPYAVSFKGHHPTSDFPKWGDFFTIAPMTRYAKDLPLLLKCM-------SDPTG 307

Mouse   310 PPLPFREEIYRSSRPLRVG---YYETDN---YTMPTP-----------------AMRRAVMETKQ 351
            |.|..       .||:.|.   ::..||   ..|..|                 |.|..:.:.|.
  Fly   308 PKLTL-------DRPISVNGIRFFFMDNDGPSGMMRPLSRDLHAAINRVATDFNAKRVNIRKMKW 365

Mouse   352 SLEAAGHTLVPFLPNNIPYALEVLSAGG------------LFSDGGCS----------FLQNFKG 394
            ||:.:...::..  .||.........|.            .|   |||          .||||..
  Fly   366 SLDISLSAMLTM--KNIETIYHKTEEGEQPKTVCKETVKYFF---GCSDSILPSVIFGHLQNFMK 425

Mouse   395 DFVDP-----CLGDLVLVLKLPRWFKKLL---SFLLKPLFPRLAAFLNSMCPRSAEKLWELQHEI 451
              :.|     .|..::..||..  ||::|   ...|.|.|           |.:|.:.:::.|::
  Fly   426 --IIPNSRHKHLASIIEALKTE--FKEMLGNDGVFLYPTF-----------PNTAHQHYQIYHKL 475

Mouse   452 EMYRQSVIAQWKAMNLDVVLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPVTTVTAED 516
                               |.||                  |..::|.|.     :|||......
  Fly   476 -------------------LEPM------------------YMAIFNTLG-----LPVTNCMIGL 498

Mouse   517 DAQMEHYKGYFGDMWDNILKKGMKKGIGLPVAVQCVALPWQEELCLRFMREVER 570
            |.:                        .||:.:|.||.|.|:.|.|...||:||
  Fly   499 DRR------------------------NLPMGIQVVANPGQDHLSLAVAREMER 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Faah	NP_034303.3	Amidase	95..562	CDD:279733	129/537 (24%)
		Substrate binding. /evidence=ECO:0000250	238..241		2/2 (100%)
CG5191	NP_650893.2	GatA	61..537	CDD:223232	140/571 (25%)
		PRK07488	63..537	CDD:236030	139/568 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I6507
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	142	1.000	Inparanoid score	I4451
Isobase	1	0.950	-	0.69812	Normalized mean entropy	S4795
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42825
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1914
SonicParanoid	1	1.000	-	-		X256
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.840