Protein Alignment CRX and otp

DIOPT Version :9

• Sequence 1: NP_000545.1
• Gene: CRX / 1406
• HGNCID: 2383
• Length: 299
• Species: Homo sapiens
• Sequence 2: NP_001286654.1
• Gene: otp / 37364
• FlyBaseID: FBgn0015524
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 73/265 - (27%)
• Similarity: 105/265 - (39%)
• Gaps: 88/265 - (33%)

Human    38 KQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQK 102
            ||:|.||.||.:||.|||..|:||.|||::.|||:|::|.|.||||||||:|||||.:::::
  Fly   115 KQKRHRTRFTPAQLNELERCFSKTHYPDIFMREEIAMRIGLTESRVQVWFQNRRAKWKKRKK--- 176

Human   103 QQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVA--------- 158
                                     :|:|...|..:..|:..|   |.|:..|.:|
  Fly   177 -------------------------TTNVFRTPGALLPSHGLP---PFGANITNIAMGDGLCGTG 213

Human   159 --------------TVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYG 209
                          |.........|||..:..:|| .||.::                  .||.|
  Fly   214 MFGGDRWSVGVNPMTAGFGQLNQSSPLSSSLNSGL-NSGINM------------------GSALG 259

Human   210 SPSSYFSGLDPYLSPMVPQ--LGGPALSPLSGPS-------------VGPSLAQSPTSLSGQSYG 259
            :.|....||:.....|:.|  :||.:..|...||             ..|.|:..|.|...:..|
  Fly   260 AGSYQHYGLNALGDSMMYQHSVGGVSCGPSGSPSATTPPNMNSCSSVTPPPLSAQPNSSQNELNG 324

Human   260 AYSPV 264
            ...|:
  Fly   325 EPMPL 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRX	NP_000545.1	Homeobox	43..93	CDD:395001	32/49 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..155		8/61 (13%)
		TF_Otx	166..249	CDD:397546	22/97 (23%)
otp	NP_001286654.1	Homeobox	119..167	CDD:278475	29/47 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	100	1.000	Inparanoid score	I5000
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960