Protein Alignment CRX and Crx

DIOPT Version :10

• Sequence 1: NP_000545.1
• Gene: CRX / 1406
• HGNCID: 2383
• Length: 299
• Species: Homo sapiens
• Sequence 2: NP_001106801.1
• Gene: Crx / 12951
• MGIID: 1194883
• Length: 323
• Species: Mus musculus
• Alignment Length: 299
• Identity: 289/299 - (96%)
• Similarity: 291/299 - (97%)
• Gaps: 0/299 - (0%)

Human     1 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPD 65
            |||||||||||||||||||||:||||||||||.||||||||||||||||||||||||||||||||
Mouse    25 MMAYMNPGPHYSVNALALSGPNVDLMHQAVPYSSAPRKQRRERTTFTRSQLEELEALFAKTQYPD 89

Human    66 VYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTD 130
            ||||||||||||||||||||||||||||||||||||||||||||.|.||||||||||||||||||
Mouse    90 VYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGAQTKARPAKRKAGTSPRPSTD 154

Human   131 VCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTY 195
            ||.|||||||||||.|||||||||||||||||||||||:||||||||||||||||||||||||||
Mouse   155 VCTDPLGISDSYSPSLPGPSGSPTTAVATVSIWSPASEAPLPEAQRAGLVASGPSLTSAPYAMTY 219

Human   196 APASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYGA 260
            |||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||..
Mouse   220 APASAFCSSPSAYASPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYST 284

Human   261 YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL 299
            |||||||||||||||||||||||||||||||||||||||
Mouse   285 YSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRX	NP_000545.1	Homeodomain	40..93	CDD:459649	52/52 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..155		57/61 (93%)
		TF_Otx	164..249	CDD:427350	82/84 (98%)
Crx	NP_001106801.1	Homeodomain	64..117	CDD:459649	52/52 (100%)
		TF_Otx	188..273	CDD:427350	82/84 (98%)