Protein Alignment Tre1 and NPY1R

DIOPT Version :10

• Sequence 1: NP_001284901.1
• Gene: Tre1 / 140439
• FlyBaseID: FBgn0046687
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_000900.1
• Gene: NPY1R / 4886
• HGNCID: 7956
• Length: 384
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 90/329 - (27%)
• Similarity: 147/329 - (44%)
• Gaps: 62/329 - (18%)

  Fly    35 TLFAAISACVFVTIGVLGNLITLLALLKSPTIREHATTAFVISLSISDLLFCSFSLPLTAVRFFQ 99
            ||..|..|.:.  :||.|||..::.:||...:| :.|...:::||.||||.....||.|.|....
Human    42 TLALAYGAVII--LGVSGNLALIIIILKQKEMR-NVTNILIVNLSFSDLLVAIMCLPFTFVYTLM 103

  Fly   100 ESWTFGTTLCKIFPVIFYGNVAVSLLSMVGITLNRYILIACHSRYSQIYKPKFITLQLLFVWAVS 164
            :.|.||..:||:.|.:...::.||:.|:|.|.:.|:.||.....:....:..::.:.:::|.||:
Human   104 DHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVA 168

  Fly   165 FLLLLPPILGIWGEMGLDEATFSCTI------------LKKEGRSIKKT--LFVIGFLLPCLVII 215
            ..|   |.| |:..| .||...:.|:            ...:...:..|  |.|:.:..|...|.
Human   169 SSL---PFL-IYQVM-TDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIF 228

  Fly   216 VSYSCIYITVLHQKKKIRNHDNFQIAAAKGSSSSGGGSYMTTTCTRKAREDNRLTVMMVTIFLCF 280
            :.|..|||     :.|.||:...::...|..||                |..|:.:|:::|.:.|
Human   229 ICYFKIYI-----RLKRRNNMMDKMRDNKYRSS----------------ETKRINIMLLSIVVAF 272

  Fly   281 LVCFLPLMLANVVDDERNTSYPWLH-IIAS-----------VMAWASSVINPIIYAASNRNYSES 333
            .||:|||.:.|.|.|       |.| |||:           :.|..|:.:|||.|...|:|:...
Human   273 AVCWLPLTIFNTVFD-------WNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRD 330

  Fly   334 IFYF 337
            :.:|
Human   331 LQFF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tre1	NP_001284901.1	7tmA_GPR84-like	37..341	CDD:320338	88/327 (27%)
		TM helix 1	37..63	CDD:320338	8/25 (32%)
		TM helix 2	71..94	CDD:320338	9/22 (41%)
		TM helix 3	109..139	CDD:320338	10/29 (34%)
		TM helix 4	153..171	CDD:320338	4/17 (24%)
		TM helix 5	195..220	CDD:320338	6/26 (23%)
		TM helix 6	264..294	CDD:320338	11/29 (38%)
		TM helix 7	302..327	CDD:320338	11/36 (31%)
NPY1R	NP_000900.1	7tmA_NPY1R	41..331	CDD:320517	89/324 (27%)
		TM helix 1	42..68	CDD:320517	10/27 (37%)
		TM helix 2	75..100	CDD:320517	10/24 (42%)
		TM helix 3	113..143	CDD:320517	10/29 (34%)
		TM helix 4	154..175	CDD:320517	6/24 (25%)
		TM helix 5	208..237	CDD:320517	9/33 (27%)
		TM helix 6	256..286	CDD:320517	12/45 (27%)
		TM helix 7	299..324	CDD:320517	6/24 (25%)