Protein Alignment Tre1 and MTNR1B

DIOPT Version :9

• Sequence 1: NP_001284901.1
• Gene: Tre1 / 140439
• FlyBaseID: FBgn0046687
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_005950.1
• Gene: MTNR1B / 4544
• HGNCID: 7464
• Length: 362
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 98/371 - (26%)
• Similarity: 164/371 - (44%)
• Gaps: 49/371 - (13%)

  Fly    24 AATQSIYPHSATLFAAISACVFVT--IGVLGNLITLLALLKSPTIREHATTAFVISLSISDLLFC 86
            :|..|..|....:..|:||.:.||  :.|:|||:.:|::|::..:| :|...|::||:::||:..
Human    27 SARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLR-NAGNLFLVSLALADLVVA 90

  Fly    87 SFSLPLTAVRFFQESWTFGTTLCKIFPVIFYGNVAVSLLSMVGITLNRYILIACHS-RYSQIYKP 150
            .:..||..|..|.:.|..|...||....:...:|..|:.::..|.:|||..| ||| .|.:||:.
Human    91 FYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYI-CHSMAYHRIYRR 154

  Fly   151 KFITLQLLFVWAVSFLLLLPPILGIWGEMGLDEATFSCTILKKEGRSIKKTLFVIGFLLPCLVII 215
            ....|.:..:|.::.:.|||..  ..|.:..|...:|||.::.........:.||.||||..|:.
Human   155 WHTPLHICLIWLLTVVALLPNF--FVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVS 217

  Fly   216 VSYSCIYITVLHQKKKIRNHDNFQIAAAKGSSSSGGGSYMTTTCTRKAREDNRLTVMMVTIFLCF 280
            ..|..|::.||..::|           ||..|         ..|.:.:  |.|..:.|..:|:.|
Human   218 FCYLRIWVLVLQARRK-----------AKPES---------RLCLKPS--DLRSFLTMFVVFVIF 260

  Fly   281 LVCFLPL----MLANVVDDERNTSYP-WLHIIASVMAWASSVINPIIYAASNRNYSESIFYFRVA 340
            .:|:.||    :...:...|.....| .|.:.:.::|:.:|.:|.|:|...|:|       ||..
Human   261 AICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQN-------FRRE 318

  Fly   341 YYKIFALLKFWGEPLSPMPSRNYHQSKNSKELSGVIRSTPLFHAVQ 386
            |.:|  ||..|.      |......:.......|:....|....||
Human   319 YKRI--LLALWN------PRHCIQDASKGSHAEGLQSPAPPIIGVQ 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tre1	NP_001284901.1	7tm_1	52..323	CDD:278431	74/276 (27%)
MTNR1B	NP_005950.1	7tm_4	48..>192	CDD:304433	45/147 (31%)
		7tm_1	57..308	CDD:278431	74/276 (27%)
		7tm_4	<131..>261	CDD:304433	41/154 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24228
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4597
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.040