DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tre1 and Gpr25

DIOPT Version :9

Sequence 1:	NP_001284901.1	Gene:	Tre1 / 140439	FlyBaseID:	FBgn0046687	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001094986.1	Gene:	Gpr25 / 383563	MGIID:	2686146	Length:	358	Species:	Mus musculus

Alignment Length:	315	Identity:	64/315 - (20%)
Similarity:	119/315 - (37%)	Gaps:	54/315 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 PHSATLFAAISACVFVTIGVLGN--LITLLALLKSPTIREHATTAFVISLSISDLLFCSFSLPLT 93
            |:...:..|:....| .:|:.||  ::.||:..:.|   ......||:.|:.:||.|. .:|||.
Mouse    36 PYGHAIIPALYLAAF-AVGLPGNAFVVWLLSRQRGP---RRLVDTFVLHLAAADLGFV-LTLPLW 95

  Fly    94 AVRFFQES-WTFGTTLCKIFPVIFYGNVAVSLLSMVGITLNRYILIACHSRYSQIYKPKFITLQL 157
            |....:.. |.||..|||:.............|.:.|::::||:.:........:...:.:....
Mouse    96 AAAEARGGLWPFGDGLCKVSSFALAVTRCAGALLLAGMSVDRYLAVGRPLSARPLRSARCVRAVC 160

  Fly   158 LFVWAVSFLLLLPPILGIWGEMGLDEATFSCTILKKEG-RSIKKTLFVIGFLLPCLVIIVSYSCI 221
            ...||.:||..||.:|....:..||.....|.....|. :.:...|.::.|.||..|.::.|..:
Mouse   161 GAAWAAAFLAGLPALLYRGLQPSLDGVGSQCAEEPWEALQGVGLLLLLLTFALPLAVTLICYWRV 225

  Fly   222 YITVLHQKKKIRNHDNFQIAAAKGSSSSGGGSYMTTTCTRKAREDNRLTVMMVTIFLCFLVCFLP 286
                                              :....|..|..:....::.|:...|:.|:||
Mouse   226 ----------------------------------SRRLPRVGRARSNSLRIIFTVESVFVGCWLP 256

  Fly   287 L-MLANVVDDERNTSYP----------WLHIIASVMAWASSVINPIIYAASNRNY 330
            . :|.::....|..:.|          |...:.:.:|:.:|..||:||...:|::
Mouse   257 FGVLRSLFHLARLQALPLPCSLLLALRWGLTVTTCLAFVNSSANPVIYLLLDRSF 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tre1	NP_001284901.1	7tm_1	52..323	CDD:278431	57/285 (20%)
Gpr25	NP_001094986.1	7tm_1	56..304	CDD:278431	57/285 (20%)
Gpr25	NP_001094986.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	339..358
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24228
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100