Protein Alignment Tre1 and Gpr25

DIOPT Version :9

• Sequence 1: NP_001284901.1
• Gene: Tre1 / 140439
• FlyBaseID: FBgn0046687
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: XP_038947255.1
• Gene: Gpr25 / 363993
• RGDID: 1311611
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 312
• Identity: 76/312 - (24%)
• Similarity: 129/312 - (41%)
• Gaps: 48/312 - (15%)

  Fly    31 PHSATLFAAISACVFVTIGVLGN--LITLLALLKSPTIREHATTAFVISLSISDLLFCSFSLPLT 93
            |:|..:.:|:....|| :|:.||  ::.||:..:.|   ......||:.|:.:||.|. .:|||.
  Rat    37 PYSHAIISALYLAAFV-VGLTGNTFVVWLLSRRRRP---RRLVDTFVLHLAAADLGFV-LTLPLW 96

  Fly    94 AVRFFQES-WTFGTTLCKIFPVIFYGNVAVSLLSMVGITLNRYILIACHSRYSQIYKPKFITLQL 157
            ||...:.. |.||..||||.............|.:.|::::||:.:........:...:.:....
  Rat    97 AVAEARGGLWPFGDGLCKISSFALAATRCAGALLLAGMSVDRYLAVGRPLNARPLRSARCVRASC 161

  Fly   158 LFVWAVSFLLLLPPILGIWGEMGLDEATFSCTILKKEG-RSIKKTLFVIGFLLPCLVIIVSYSCI 221
            ..|||.:||..||.:|....:..||.....|.....:. :.:...|.::.|.||   :.|:.:|
  Rat   162 SAVWAAAFLAGLPTLLYRRLQPSLDGEGSQCAEEPSDALQGVGLLLLLLTFALP---LAVTLTC- 222

  Fly   222 YITVLHQKKKIRNHDNFQIAAAKGSS--------SSGGGSYMTTTCTRKAREDNRLTVMMVTIFL 278
            |..|..:..::|.        |:|:|        |...||::..:..|......||..:.
  Rat   223 YWRVSRRLLRVRR--------ARGNSLRIIFTVESVFVGSWLPFSILRALFYLARLRALP----- 274

  Fly   279 CFLVCFLPLMLANVVDDERNTSYPWLHIIASVMAWASSVINPIIYAASNRNY 330
              |.|.|.|.|.            |...:|:.:|:..|..||:||...:|::
  Rat   275 --LPCSLLLALR------------WGLTVATCLAFVHSCANPVIYLLLDRSF 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tre1	NP_001284901.1	7tm_1	52..323	CDD:278431	67/282 (24%)
Gpr25	XP_038947255.1	7tm_GPCRs	42..315	CDD:421689	74/307 (24%)
		TM helix 1	42..68	CDD:410628	8/26 (31%)
		TM helix 2	75..100	CDD:410628	11/25 (44%)
		TM helix 3	113..143	CDD:410628	7/29 (24%)
		TM helix 4	156..177	CDD:410628	7/20 (35%)
		TM helix 5	200..223	CDD:410628	6/26 (23%)
		TM helix 6	235..265	CDD:410628	7/37 (19%)
		TM helix 7	284..309	CDD:410628	8/36 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24228
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100