Protein Alignment Tre1 and tkr-3

DIOPT Version :10

• Sequence 1: NP_001284901.1
• Gene: Tre1 / 140439
• FlyBaseID: FBgn0046687
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_001343603.1
• Gene: tkr-3 / 177285
• WormBaseID: WBGene00006428
• Length: 400
• Species: Caenorhabditis elegans
• Alignment Length: 377
• Identity: 81/377 - (21%)
• Similarity: 166/377 - (44%)
• Gaps: 61/377 - (16%)

  Fly    44 VFVTIGVLGNLITLLALLKSPTIREHATTAFVISLSISDLLFCSFSLPLT-AVRFFQESWTFGTT 107
            :...:.|:|||:.|...|....:|. .||.|:::|..:||....|::|.. ....||| |....:
 Worm    55 IIAFMAVVGNLLVLYITLFRLRVRS-ITTYFILNLGFADLFTGIFAIPFKFQAALFQE-WFLPRS 117

  Fly   108 LCKIFPVIFYGNVAVSLLSMVGITLNRYILIACHSRYSQIYKPKFITLQLLFVWAVSFLLLLPPI 172
            ||:|.|.:....:.||:.::|...::.:..: ..|:.||: .|:.....:|.:|.::.|:.||
 Worm   118 LCRIVPYVETVALTVSVFTLVTSAVHEFRTM-FFSKCSQM-SPRSAKRCVLLIWIMAVLVSLP-- 178

  Fly   173 LGIWGEMGLDEATF-----------SCTILKKEG---RSIKKTLFVIGFLLPCLVIIVSYSCIYI 223
                  .||...|:           .|..:..:.   ::....|.:|.:.:|.:::..:|:.|.:
 Worm   179 ------HGLFHNTYEFPDDNNTSIVQCLPVYPDAGWWKTYNVYLVIIQYFVPMIILDTAYTMIAV 237

  Fly   224 TVLHQKKKIRNHDNFQIAAAKGSSSSGGGSYMTTTCTRKAREDNRLTVMMVTIFLCFLVCFLPL- 287
            .:....:.....|..::|..|.|..|     |.:..|:.    ::|...::.:..||.:|:.||
 Worm   238 KIWSLSQSRVELDETKMATQKISVVS-----MVSPNTQL----SQLMRTLIIVVACFSLCWFPLE 293

  Fly   288 --MLANVVDDERNTSYPWLHIIASVMAW---ASSVINPIIYAASNRNYSESIFYFRVAYYKIFAL 347
              :|.|.:..|.| .:.:::::.....|   ::|.:|||||...|..|:|.       |.::|..
 Worm   294 TYLLLNELKPEIN-GWKYINLVFFFSHWLAMSNSCLNPIIYGLYNTKYNEE-------YRRLFRQ 350

  Fly   348 LK-FWGEPL----SPMPSRNYHQS---KNSKELSGVIRSTPLFHAVQKNSIN 391
            :. .|....    |..|.|.::.|   ::.:|:..::...|:   :..|:::
 Worm   351 IGCIWQRQKSLDDSMKPERRWNSSNDCQDQQEIDQIVDIPPV---ISTNNLS 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tre1	NP_001284901.1	7tmA_GPR84-like	37..341	CDD:320338	71/317 (22%)
		TM helix 1	37..63	CDD:320338	6/18 (33%)
		TM helix 2	71..94	CDD:320338	8/23 (35%)
		TM helix 3	109..139	CDD:320338	6/29 (21%)
		TM helix 4	153..171	CDD:320338	4/17 (24%)
		TM helix 5	195..220	CDD:320338	4/27 (15%)
		TM helix 6	264..294	CDD:320338	8/32 (25%)
		TM helix 7	302..327	CDD:320338	7/27 (26%)
tkr-3	NP_001343603.1	7tm_GPCRs	47..344	CDD:475119	71/317 (22%)
		TM helix 1	49..73	CDD:320515	5/17 (29%)
		TM helix 2	82..104	CDD:320515	7/21 (33%)
		TM helix 3	120..142	CDD:320515	5/21 (24%)
		TM helix 4	163..179	CDD:320515	5/23 (22%)
		TM helix 5	210..233	CDD:320515	3/22 (14%)
		TM helix 6	275..297	CDD:320515	5/21 (24%)
		TM helix 7	312..337	CDD:320515	7/24 (29%)