DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Etv2 and pnt

DIOPT Version :9

Sequence 1:	XP_006539604.1	Gene:	Etv2 / 14008	MGIID:	99253	Length:	358	Species:	Mus musculus
Sequence 2:	NP_524461.2	Gene:	pnt / 42757	FlyBaseID:	FBgn0003118	Length:	718	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	101/284 - (35%)
Similarity:	129/284 - (45%)	Gaps:	74/284 - (26%)

- Green bases have known domain annotations that are detailed below.

Mouse   131 PGTSPSPFVGF-EGATGQNPAT--SAGGVPSWSHPPAAWSTTSWDCSVGPSGATYWDNGLGGEA- 191
            |||......|: .|:..||..|  |:.|:|:..   ||:...|   ..||:|..  .:|.||:.
  Fly   431 PGTQNGNIGGYGGGSNSQNDPTDLSSYGLPAHL---AAYGGGS---GSGPTGGR--SSGGGGDES 487

Mouse   192 ----------HEDYKMSWG-GSAGSDYTTTWNT-GLQDCSIPFEGHQS----------PAFTTPS 234
                      |:..:.|.| ||.|:...:|.|: |..|.|..|.|..:          |.||...
  Fly   488 DYHSTISAQDHQSQQSSGGNGSGGASGGSTGNSNGYLDSSSEFYGSYAGRNRFHDGYPPEFTPYD 552

Mouse   235 KSNKQS-----------------------------DRATLTRYSKT------NHRGPIQLWQFLL 264
            ..:.||                             |:..|..|:..      ...||||||||||
  Fly   553 AQSFQSMGPQPTAMDQWGAAHAHQHPAAYMSTLGLDKGLLGGYTTQGGVPCFTGSGPIQLWQFLL 617

Mouse   265 ELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSGG 329
            |||.|....|.|.|||:..||:|.||.||||.||.||.||.||||||||||||||.::|:.|:.|
  Fly   618 ELLLDKTCQSFISWTGDGWEFKLTDPDEVARRWGIRKNKPKMNYEKLSRGLRYYYDKNIIHKTAG 682

Mouse   330 RKYTYRFGGRVPVLAYQDDMGHLP 353
            ::|.|||     |...|:.:||.|
  Fly   683 KRYVYRF-----VCDLQNLVGHTP 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Etv2	XP_006539604.1	ETS	256..338	CDD:197710	54/81 (67%)
pnt	NP_524461.2	SAM_PNT-ETS-1,2	179..250	CDD:188879
pnt	NP_524461.2	ETS	609..693	CDD:197710	55/88 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11849
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910