Protein Alignment CRMP1 and CG6106

DIOPT Version :10

• Sequence 1: XP_054204940.1
• Gene: CRMP1 / 1400
• HGNCID: 2365
• Length: 713
• Species: Homo sapiens
• Sequence 2: NP_573287.1
• Gene: CG6106 / 32816
• FlyBaseID: FBgn0030914
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 508
• Identity: 124/508 - (24%)
• Similarity: 210/508 - (41%)
• Gaps: 95/508 - (18%)

Human   128 SDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEAN---------GRMVI-PG 182
            |...||.||.|::           .:|:|:::   |..|..|.|...|         |.:|: ||
  Fly    16 SQNALIHGGIIVD-----------TEGIIRRV---LRSPQEVNTYLYNTESESVYDFGDLVLMPG 66

Human   183 GIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCC 247
            .||.|.::.:|  |....:.|...|:||..||.|.|||    .|.::...:....|..|.| |..
  Fly    67 LIDPNVHINEP--GRKDWEGFATATKAAAAGGFTTIID----RPTNAQPPTVSVAHLKAKT-STA 124

Human   248 DYSLHVDITSW---YDGVREELEVLVQDKGVNSFQVYM------AYKDVYQMSDSQLYEAFTFL- 302
            ...::||:..|   ..|..::|..|: ..||...|..:      ..::...:::|||.||.:.|
  Fly   125 RGKIYVDVGFWGGLVPGNGDQLAALL-GAGVMGLQCTLCDPAAPVSQEFPAVNESQLEEALSQLD 188

Human   303 ----KGLGAVILVHAENGDL-----IAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAG 358
                :| .|::.||||   |     |..:::...|.|.     ..::||.::|..|......:|.
  Fly   189 KDQAEG-EAIVAVHAE---LPLTTEIHPDEEAPREYGT-----FLVTRPPQMEISATQLLCRLAN 244

Human   359 R--INCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDG-THYWSKNWAKAA------- 413
            |  ..| ::|....|..:..::...|::|         .:|..|. .||    .|.||
  Fly   245 RHPRRC-IHILNCSSGESLPLVEECRRQG---------GNLTVDTCPHY----LALAAEDVPDCG 295

Human   414 -AFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAV----GKDNFTLIPEGVNGIE 473
             .|.|.||:...........:|...|.:::.||.|.|.:...:|:    |:.||.....|:|.::
  Fly   296 TEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAWPGINSLQ 360

Human   474 ERMTVVWDKAVATGKMDENQFVA----VTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTI 534
            ..::||| .|.|..:...|..:|    :.....|.:..|...|||||.|.|||..:|.|::..|:
  Fly   361 LSLSVVW-TAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSPEEEFTV 424

Human   535 TAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKA 587
            ..:...:|.:...:.|.:..|.....:.:|..|::... ...:.:|:.:.|::
  Fly   425 GPELLYTATKATPYAGQKLRGVVHATVVRGLHVYQQFE-GFGQPLGKVLLRRS 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP1	XP_054204940.1	D-HYD	131..580	CDD:238639	121/496 (24%)
CG6106	NP_573287.1	L-HYD_ALN	2..473	CDD:238640	123/503 (24%)