Protein Alignment CRKL and crkl

DIOPT Version :9

• Sequence 1: NP_005198.1
• Gene: CRKL / 1399
• HGNCID: 2363
• Length: 303
• Species: Homo sapiens
• Sequence 2: NP_989060.1
• Gene: crkl / 394657
• XenbaseID: XB-GENE-976114
• Length: 289
• Species: Xenopus tropicalis
• Alignment Length: 268
• Identity: 206/268 - (76%)
• Similarity: 226/268 - (84%)
• Gaps: 15/268 - (5%)

Human     1 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65
            ||||||||||||.||.|||||||||:||||||||:||||||||||||:|||||||||||||||||
 Frog     1 MSSARFDSSDRSGWYFGPVSRQEAQSRLQGQRHGVFLVRDSSTCPGDHVLSVSENSRVSHYIINS 65

Human    66 LPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRT 130
            ||.||:||||||||:|||||:|||||||||||||||||||||||:|:.:||::|..|:|||||||
 Frog    66 LPGRRYKIGDQEFDNLPALLDFYKIHYLDTTTLIEPAPRYPSPPVGTGTAPSVPVPEENLEYVRT 130

Human   131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNS 195
            ||||||||||||||||||||||:||||||||||||||||:|||||||||||.|.|.|||.|||||
 Frog   131 LYDFPGNDAEDLPFKKGEILVIVEKPEEQWWSARNKDGRIGMIPVPYVEKLSRLSLHGKMGNRNS 195

Human   196 NSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEV 260
            |||||||||||||||||.:|||| |.:|.|.|.           .||....| ..:...|:.:.|
 Frog   196 NSYGIPEPAHAYAQPQTPSPLPA-SSTPPAVIQ-----------FKAGSGAV-SGHGSAAIIVLV 247

Human   261 GD--IVKV 266
            ||  |:||
 Frog   248 GDGQILKV 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRKL	NP_005198.1	SH2_CRK_like	6..106	CDD:198180	90/99 (91%)
		SH3_CRK_N	126..180	CDD:212692	51/53 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..234		34/49 (69%)
		SH3_CRK_C	237..293	CDD:212693	10/32 (31%)
crkl	NP_989060.1	SH2_CRK_like	6..106	CDD:198180	90/99 (91%)
		SH3_CRK_N	126..180	CDD:212692	51/53 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I21986
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38021
Inparanoid	1	1.050	557	1.000	Inparanoid score	I6966
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52661
OrthoDB	1	1.010	-	-		D1414461at2759
OrthoFinder	1	1.000	-	-		FOG0003539
OrthoInspector	1	1.000	-	-		oto156651
Panther	1	1.100	-	-	LDO	PTHR19969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2415
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080