Protein Alignment RBMXL3 and nono-1

DIOPT Version :9

• Sequence 1: NP_001138818.1
• Gene: RBMXL3 / 139804
• HGNCID: 26859
• Length: 1067
• Species: Homo sapiens
• Sequence 2: NP_498295.3
• Gene: nono-1 / 175844
• WormBaseID: WBGene00017778
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 109/491 - (22%)
• Similarity: 150/491 - (30%)
• Gaps: 150/491 - (30%)

Human     9 KLFIGGLNLKTDEKALKAEFGKYGHIIKVFLMKDRKTNKSRGFAFVTFESPADAKAAARDMNGKY 73
            :||:|.|..:..|..||..|..:|.|.:.:|       ..:||||:..::.|.|::|...::|:.
 Worm   117 RLFVGNLPNEVKETELKELFSPHGDIAECYL-------SGKGFAFLRLDTRAHAESAKEAIDGRI 174

Human    74 LDGKAIMVAQTIKPAFKSSRWVPPTPGS----------GSRSRFSHRTRGGGSSPQRPPSQG--- 125
            :.|:.:.|...:..|....:.:.||..:          |...|..|.....|    ||..:|
 Worm   175 IHGRQVRVRFAVHGAAIRVKELSPTVSNEMLYHAFSHFGDVERAVHIVDEKG----RPTGEGIVE 235

Human   126 ---RPDDGRGYAGYFD----LWPYRAPM-------------------PRKRGPPPRHWASPPHKR 164
               :|:.....|...|    |.....|:                   ||..|........|  :.
 Worm   236 FERKPNCNEAMAAIRDKVFLLTASPKPLICEVLEPRDEDDGLAERMIPRTPGLSKERELGP--RF 298

Human   165 ATPSSLAHSVGCGMRGKAPTVSGQD----------------------GYSGLQ--------PRRW 199
            .||:|..:..  ||:.|...|..|.                      .|...|        .||.
 Worm   299 PTPNSFEYVY--GMKWKELYVVEQKRRAQLDEELRESRRRLESDMELAYQDYQAQMLREDLQRRQ 361

Human   200 AGPPHKRAVPRSSLARIGG--SGMPGKAP------------AVWGQDGYSGPRVREPLPPCRDPG 250
            .......|..|..:..:||  .||||..|            ...|..|..||      ||...|.
 Worm   362 QELERLEAARRERMRGLGGPPPGMPGGVPPQAQPFNPHGGSMFGGPGGPGGP------PPFGQPF 420

Human   251 DFVPALRDYSRRYYGHSSVP-DYRPLRGDGNQNGYRGRDHEYTDHPSKGSYREP--LKSYGGPCG 312
            ...|         .|..:|| ...||.|.|...  ||........|..|....|  ....|||.|
 Worm   421 QQAP---------QGMFNVPTGPPPLMGGGGDP--RGPPGGMGGPPGHGGMGGPPGHGGQGGPPG 474

Human   313 AAPVWGTPPSYGG----------GCRYEEYQGNSPDACSEG--------RSSEALPVVLPDAYSR 359
            ...:.|.||..||          |....:..|.|  ...||        :|....|..:|   .|
 Worm   475 HGGMGGPPPGQGGPGGPGGPGGPGGMLPKSHGRS--NMIEGVQRLLQIFKSDNGPPGGMP---GR 534

Human   360 DHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGR 395
            |:.|:...||...|         ||:.|...|.:.|
 Worm   535 DYPPQQGPGGMFGS---------YGDGGYPPEKKQR 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBMXL3	NP_001138818.1	RRM	<1..>81	CDD:223796	20/71 (28%)
		RRM_RBMX_like	7..86	CDD:240828	21/76 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..131		10/56 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..175		8/49 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	267..305		11/40 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	357..1067		11/39 (28%)
nono-1	NP_498295.3	RRM1_p54nrb_like	115..184	CDD:240778	21/73 (29%)
		RRM2_p54nrb_like	190..269	CDD:240779	14/82 (17%)
		eNOPS_SF	260..349	CDD:240579	14/92 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910