DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBMXL3 and sig-7

DIOPT Version :9

Sequence 1:	NP_001138818.1	Gene:	RBMXL3 / 139804	HGNCID:	26859	Length:	1067	Species:	Homo sapiens
Sequence 2:	NP_492343.2	Gene:	sig-7 / 172664	WormBaseID:	WBGene00000890	Length:	427	Species:	Caenorhabditis elegans

Alignment Length:	179	Identity:	47/179 - (26%)
Similarity:	79/179 - (44%)	Gaps:	35/179 - (19%)

- Green bases have known domain annotations that are detailed below.

Human     1 MMEADR--PEK-LFIGGLNLKTDEKALKAEFGKYGHIIKVFLMKDRKTNKSRGFAFVTFESPADA 62
            :.:||.  ||. ||:..||..|.::.|:..|.::|.|....:::||::..|..:||:.|::....
Worm   231 LKDADEVPPENVLFVCKLNPVTTDEDLEIIFSRFGKINNCEIVRDRRSGDSLQYAFIEFDNAKSC 295

Human    63 KAAARDMNGKYLDGKAIMV--AQTIKPAFKSSRWVPPTPGSGSRSRFSHRTRGGGSSPQRPPSQG 125
            :.|...|:...:|.:.|.|  :|::...:|..      |.|..:.....|     .||||
Worm   296 EQAFFKMDNVLIDDRRIHVDFSQSVSQNYKYK------PKSQQQEAPKRR-----QSPQR----- 344

Human   126 RPDDGRGYAGYFDLWPYRAPMP-RKRGPPP-----RHWASPPHKRATPS 168
            ||:..|.:        .|:|.| |:|.|.|     |.:...|.:|...|
Worm   345 RPEVKRSH--------QRSPSPRRRRSPSPKKDKKRDYRREPARRRRSS 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBMXL3	NP_001138818.1	RRM	<1..>81	CDD:223796	23/82 (28%)
		RRM_RBMX_like	7..86	CDD:240828	23/81 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..131		10/40 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	144..175		10/31 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	267..305
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	357..1067
sig-7	NP_492343.2	cyclophilin_RRM	4..169	CDD:238902
		RRM	128..>346	CDD:223796	33/130 (25%)
		RRM_PPIL4	238..320	CDD:240681	23/81 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910