Protein Alignment UPRT and Uck

DIOPT Version :10

• Sequence 1: NP_659489.1
• Gene: UPRT / 139596
• HGNCID: 28334
• Length: 309
• Species: Homo sapiens
• Sequence 2: NP_001138105.1
• Gene: Uck / 42894
• FlyBaseID: FBgn0263398
• Length: 305
• Species: Drosophila melanogaster
• Alignment Length: 306
• Identity: 55/306 - (17%)
• Similarity: 102/306 - (33%)
• Gaps: 128/306 - (41%)

Human    71 GSSLNSE----------GNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIRELQTI 125
            |::.|.|          |.:.||.|:               :.::|..||....|:...|::.:|
  Fly    17 GAAANDEVKSPFLIGVAGGTASGKST---------------VCKKIMEQLGQAEMDHTQRQVVSI 66

Human   126 IRDK-----------TASRGDFMFS-----ADRLIRLVVEEGL--------------NQLPYKEC 160
            .:|.           .|.:|.|.|.     .:.|:...::..|              |.|.::..
  Fly    67 SQDSFYRELTPAEKAKAQKGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENV 131

Human   161 MVTTPTGYKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKF 225
            :|..|.    :.|.||    |:.:....:         .|.:...|:.:.:|.:|:.|:    :.
  Fly   132 LVIYPA----DVVLFE----GILVFYFPK---------IRELFHMKLFVDTDSDTRLAR----RV 175

Human   226 PPDIYRR-----KVLLMY--------------------PILSTG--NTVIEAVKVLIE------- 256
            |.||..|     .||..|                    .|:..|  |||  |:.::::
  Fly   176 PRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIPRGADNTV--AIDLIVQHIRDFLN 238

Human   257 ----HGVQPSVIILLSL--------FSTPHGAK----SIIQEFPEI 286
                ||...::.:.::|        |:.|.|:.    :.|:.|..|
  Fly   239 NRSRHGSTGNMALYMNLDLNATGAGFAGPDGSNLGTYNAIRRFSTI 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UPRT	NP_659489.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38
		UPRTase	118..308	CDD:434124	44/249 (18%)
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	43/243 (18%)