Protein Alignment Ces3b and CG4382

DIOPT Version :9

• Sequence 1: NP_653094.2
• Gene: Ces3b / 13909
• MGIID: 3644960
• Length: 571
• Species: Mus musculus
• Sequence 2: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 174/636 - (27%)
• Similarity: 257/636 - (40%)
• Gaps: 146/636 - (22%)

Mouse    16 VWVTCLLLAFVTTVTG-----------PKVIQPEVD--------------TPLGRVRGRQVGVKD 55
            :|..|   .||..:.|           .|.|..|.|              |.||::|| .:....
  Fly     1 MWRLC---GFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRG-TILPSQ 61

Mouse    56 TDRMVNVFLGIPFAQAPVGPLRFSAPLPPQPWEGVRDASINPPMCLQDVEKMINSRFGLNEKIKI 120
            :.|....|.|||:|:.||..|||..|.|.:.|....||:.:.|.|.|         .||...
  Fly    62 SGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ---------LGLVSG--- 114

Mouse   121 FPISEDCLTLNIYS---PTEITAGDKRPVMVWIHGGSL--LVGSSTSQDGSALAAYGDVVVVTVQ 180
             .:|||||.:|||:   |:|.....:|||:|:||.|..  |.|.|.:..|........:|:||..
  Fly   115 -DVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFN 178

Mouse   181 YRLGIFGFLSTGDKHMPGNRGFLDVVAALRWVQGNIAPFGGDPNCVTIFGNSAGGMIVSSLFLSP 245
            ||||..|||:||.:..|||.|..|.|..||||:.:|:.|||||:.:|:.|..||.|.|:...:||
  Fly   179 YRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSP 243

Mouse   246 ISAGLFHRAISQSGIVTTIMMEDMKPW--PE-----AQNFANSVACGSASPAELVQCLLQKEGKD 303
            :|.||||:||..||.||       ..|  |:     |...|..:.|.:.:..|::.||   :||.
  Fly   244 MSRGLFHKAIVMSGAVT-------GQWSLPDHQMDVATKQATLLHCHTENVTEMMDCL---KGKH 298

Mouse   304 LIKQKNV---------NISYIV----------NDSFFPQRPEKLLADQQFPTVPYLLGVTNHEFG 349
            .::..|.         |...|:          .:.|..:.|.:...:..|..||.:.|:|..||
  Fly   299 YLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEF- 362

Mouse   350 WLLLKSLNILDKLEHLSREDLLEISRPFLAIMEVPPEIMPTVIDEYLDNGSD-------QSATRY 407
              :..:|:||.....||            |:.|....:.|..   ::.|.||       |....:
  Fly   363 --VGPALSILQSPTLLS------------ALNENFESLAPVF---FMYNTSDARACNISQELRNH 410

Mouse   408 AFQELLGDISFIIPTLN--FSKYLRDAG-----------CPVFLYEFQHTPSSFAKFKP--AWVK 457
            .|.:.|.|.:..:..|:  :|..|...|           ..|:.|.|.:..:....:.|  |...
  Fly   411 YFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTKVYYYRFSYQGARSHIYYPEDAPYG 475

Mouse   458 ADHASENSFVFGGPFLTDESSLLAFPEATEEEKQLSLTMMAQWSQFARTGNPNGKGLPP------ 516
            ..|..:..::|..|.::     ..|.|..:|.:.:.: |:..:|.||..|:||    .|
  Fly   476 VVHHDDLMYLFVEPSIS-----RMFTEDDDEFRMVDI-MVRMFSAFAYKGDPN----KPTDLALR 530

Mouse   517 ---W-PQLNQLEQYLEIGLESRTGVKLKKGRLQFWTETLPRKIQEWHREQR 563
               | |...:...||:||........|.....:.|....|   ..|.|:.:
  Fly   531 DIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP---LNWRRQTK 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ces3b	NP_653094.2	COesterase	36..547	CDD:278561	163/587 (28%)
		Aes	75..>245	CDD:223730	68/174 (39%)
		Prevents secretion from ER. /evidence=ECO:0000255	568..571
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	161/575 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832497
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.890