Protein Alignment Ces1e and CG4382

DIOPT Version :9

• Sequence 1: NP_598421.1
• Gene: Ces1e / 13897
• MGIID: 95432
• Length: 562
• Species: Mus musculus
• Sequence 2: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Alignment Length: 609
• Identity: 173/609 - (28%)
• Similarity: 266/609 - (43%)
• Gaps: 104/609 - (17%)

Mouse     1 MCLSALILVSLAA----------------FTAGAGHPSSPPMVDTVQGKVLGKYISLEGFTQPVA 49
            :|...|:|..||:                ...|:....|..::.|..||:.|..:..:......|
  Fly     4 LCGFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQSGRNFYA 68

Mouse    50 VFLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYPPMCFQDPVTGQIVNDLLTNRKEKIPLQFS 114
             |.|:|:||||:..|||.||:|.|.|....:||...|.|   |..|.:..|:            |
  Fly    69 -FRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKC---PQLGLVSGDV------------S 117

Mouse   115 EDCLYLNIYT---PADLTKSDRLPVMVWIHGGGL--VLGGASTYDGLVLSTHENVVVVVIQYRLG 174
            ||||.:||||   |::...:.|.||:|:||.||.  :.|.:..:.|.....:..:|:|...||||
  Fly   118 EDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLG 182

Mouse   175 IWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIAKFGGDPGSVTIFGESAGGESVSVLVLSPLAKN 239
            ..||.:||...:.||.|..|||..|.||:.:|::|||||.|:|:.|..||..:|::.::||:::.
  Fly   183 SLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRG 247

Mouse   240 LFQRAISESGVALTAGLVKKNTRPLAEKIAVISGCKNTTSAAMVHCLRQKTEEELLGTTLKLNLF 304
            ||.:||..||.......:..:...:|.|.|.:..|.......|:.||:.|...|...|..|  :|
  Fly   248 LFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPK--MF 310

Mouse   305 KLDLHGDSRQSHPFVPTVLDGVLLPKMPEE-ILAEK--------NFNTVPYIVGINKQEFGWILP 360
            :.|      :::|.:  :...|:.|...:| .|.|:        :|..||.|.|:.|.||
  Fly   311 EFD------RNNPLI--LWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEF----- 362

Mouse   361 TMMNYPPSDVKLDQMTAMSLLKKS------SFLLNLPEDAIAVAIEKYLRDKDY------TGRNK 413
                ..|:...|...|.:|.|.::      .|.:....||.|..|.:.||:..:      ..|:.
  Fly   363 ----VGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRSL 423

Mouse   414 DQLLELIGDVV--FGVPSVIVSRGHRDA-GAPTYMYEFQY----SPSFSSEMKPDTVVGDHGDEI 471
            :.|..|..|.:  ||:...:    |..| ....|.|.|.|    |..:..|..|..||  |.|::
  Fly   424 EALSNLYSDALTGFGIHRFV----HLAARSTKVYYYRFSYQGARSHIYYPEDAPYGVV--HHDDL 482

Mouse   472 YSVFGAP-ILRGGT-SEEEINLSKMMMKFWANFARNGNPNGQGLP--------HWPEYD-QKEGY 525
            ..:|..| |.|..| .::|..:..:|::.::.||..|:||   .|        .|..:. :|..|
  Fly   483 MYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPN---KPTDLALRDIRWRPFSFKKRYY 544

Mouse   526 LQIGATTQQAQKLKEKEVAFWTEL 549
            |.||......:.|..:....|..|
  Fly   545 LDIGKHITLEENLNAENYEIWKRL 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ces1e	NP_598421.1	COesterase	25..546	CDD:278561	164/564 (29%)
		Aes	44..>242	CDD:223730	77/202 (38%)
		Prevents secretion from ER. /evidence=ECO:0000255	559..562
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	165/567 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832970
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.900