Protein Alignment Erg and Ets97D

DIOPT Version :10

• Sequence 1: NP_598420.1
• Gene: Erg / 13876
• MGIID: 95415
• Length: 486
• Species: Mus musculus
• Sequence 2: NP_001263000.1
• Gene: Ets97D / 43236
• FlyBaseID: FBgn0004510
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 438
• Identity: 135/438 - (30%)
• Similarity: 208/438 - (47%)
• Gaps: 88/438 - (20%)

Mouse     2 IQTVPDP----AAH--IKEALSVVSE--DQSLFECA-YGTPHLAKTEMTASSSSDYGQTSK---- 53
            ::|..:|    ..|  |:|.||::..  :|.:..|. |.|..|...:...|..:...|..|
  Fly    36 VETEAEPDDIIIVHMDIREPLSMLKSLVEQKIGVCLNYYTFWLQDAQELESHKNLVDQCVKGEGL 100

Mouse    54 ---------MSPRVPQQDWLSQAPARVTIKME-----CNPSQVNGSRNSPDECSVNKGGKMVGSP 104
                     :..|:...|.|....|.:....|     .:|.:....::|..|..:....|.:...
  Fly   101 VQINVQIQTIRKRINIADVLKPTEAALAALAEEVVGQLSPPETASQKSSSSESPIKTPLKRMHKE 165

Mouse   105 DTVGMSYGSYMEEKHVPP-------PNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLLDV 162
            |:...|    :|.|.|.|       ......:.|:.:|.....|:..||..|||||||::.|:.:
  Fly   166 DSEEES----VEGKDVKPVLNWVLDSKFKREQIRLKIPEAANEWTHAHVTYWLEWAVKQFELVGI 226

Mouse   163 DVLLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRE---TPLPHLTSDDVDKALQNSPR 224
            ::..:| ::|:|||.||.::|.:..|....:|..:||..|:|   ..:.|..:::..|..|  ||
  Fly   227 NMSDWQ-MNGQELCAMTHEEFNQKLPRDPGNIFWTHLQLLKECNFVSVVHKRAEEQRKPKQ--PR 288

Mouse   225 LMHAR----NTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHSHLTPQSKAAQPSPS 285
            :|.|.    |:||:..:          .|||.          |:|..:..|..:.:|..:..:||
  Fly   289 IMSANSISTNSGGSLSL----------EQRIM----------RKSYQSVKSSDSVESTTSSMNPS 333

Mouse   286 AVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTD 350
                         .|..:|       :..:||:||||||||:|:|..:::.|.|.||.||||:||
  Fly   334 -------------NYTTIG-------SGNNGQVQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTD 378

Mouse   351 PDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFD 398
            ||.|||.|||:|:||.|||:|||||||||||.::::||.|||:|||||
  Fly   379 PDRVARLWGEKKNKPAMNYEKLSRALRYYYDGDMISKVSGKRFAYKFD 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erg	NP_598420.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	41..62		4/33 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	79..99		3/19 (16%)
		SAM_superfamily	122..205	CDD:472832	28/92 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..311		11/61 (18%)
		ETS	317..400	CDD:197710	56/82 (68%)
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:463311	16/74 (22%)
		SAM_PNT-GABP-alpha	184..272	CDD:176084	27/88 (31%)
		ETS	345..429	CDD:197710	56/82 (68%)