DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ARID3C and sol1

DIOPT Version :9

Sequence 1:	NP_001017363.1	Gene:	ARID3C / 138715	HGNCID:	21209	Length:	412	Species:	Homo sapiens
Sequence 2:	NP_595529.1	Gene:	sol1 / 2540318	PomBaseID:	SPBC30B4.04c	Length:	865	Species:	Schizosaccharomyces pombe

Alignment Length:	394	Identity:	87/394 - (22%)
Similarity:	147/394 - (37%)	Gaps:	87/394 - (22%)

- Green bases have known domain annotations that are detailed below.

Human    15 GVGPLAPACPLLPPQPPLPDHRTLQAPEGALGNVGAEEEEDAEEDEEKREEAGAEEEAAEESRPG 79
            |.|.:..:.|:: |...:|..   |..|.|:..   ::::..::...:|:....|...:::..|.
pombe    96 GSGSVKYSSPMM-PSSRIPFQ---QEKEAAMQQ---QQQQQQQQQLYQRQMQSREALLSQQIPPN 153

Human    80 ----------------AQGPSSPSSQPPGLHPHEWTYEEQFKQLYELDADPKRKEFLDDLFSFMQ 128
                            |..|::||.....|.|   .|...|            .:|:..|.|||:
pombe   154 QIGINAHPAVRQTPQPAPSPNTPSGNANQLTP---AYAASF------------DKFMVSLISFME 203

Human   129 KRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQY 193
            |||||:...|.:....::|..|:.||...||..:|.....|.:::..|..|   :..|.:|..||
pombe   204 KRGTPIKSYPQINNTPINLMMLYALVMRAGGSRQVSAHNFWPKISASLGFP---SPDAISLLIQY 265

Human   194 M-KYLYPYECETRALSSPGELQAAIDSNRREGRRQAYTATPLFGLAGPPPRGAQDPALGPGPAPP 257
            . .||.|||            :|.:.:.:::...|...|.....:...|....|.|......|..
pombe   266 YNSYLLPYE------------EAWLAAQQQQKSLQQAKANHSANVQSRPKNYPQKPVQTTPEAVH 318

Human   258 ATQS--------SPGPAQGSTSGLPAHACAQLSPSPIKKEESGIPNPCLALPVGLALGPTREKLA 314
            |..|        ||.||..:....||      :|:.:..|.:..|.|.         .|||
pombe   319 ANGSMHGSLHSKSPSPAFTANRFSPA------APTTVSSERNAPPYPS---------APTR---- 364

Human   315 PEEPPEKRAVLMGPMDPPRPCMPPSFLPRGKVPLREERLDGPLNLAGS-GISSINMALEINGVVY 378
            |..|..:.:....|:|...|.   ::.|. |.|: :..|..|||:|.: .:....:.|::..:|.
pombe   365 PTPPTVQTSSSAAPVDSAEPV---AYQPI-KKPI-DPMLGYPLNVAATYRLDESLLRLQMPSIVD 424

Human   379 TGVL 382
            .|.:
pombe   425 LGTV 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ARID3C	NP_001017363.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..96		16/96 (17%)
		ARID	101..227	CDD:355778	32/126 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	232..278		12/53 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	388..412
sol1	NP_595529.1	BRIGHT	189..277	CDD:128777	31/114 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	58	1.000	Domainoid score	I3481
eggNOG	1	0.900	-	-		E1_KOG2744
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001099
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930