Protein Alignment ATF2 and Jra

DIOPT Version :9

• Sequence 1: NP_001243019.1
• Gene: ATF2 / 1386
• HGNCID: 784
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_001260844.1
• Gene: Jra / 36057
• FlyBaseID: FBgn0001291
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 396
• Identity: 86/396 - (21%)
• Similarity: 141/396 - (35%)
• Gaps: 83/396 - (20%)

Human   131 TTHQDSPLPHP---ESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSP 192
            |..|..|...|   |...|.:.:.|...|:.| :...||.||.:.:  .::.:..:.....:.||
  Fly    22 TAIQIIPKTEPVGEEGPMSLDFQSPNLNTSTP-NPNKRPGSLDLNS--KSAKNKRIFAPLVINSP 83

Human   193 TSSTVITQAP-------SSNRPIVPVPGP-FP------LLLHLPNGQTMPVAIPASITSSNVHVP 243
            ..|:.....|       |:|....|.||. ||      .:..|..|:....|:....|:|...
  Fly    84 DLSSKTVNTPDLEKILLSNNLMQTPQPGKVFPTKAGPVTVEQLDFGRGFEEALHNLHTNSQAF-- 146

Human   244 AAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGSGLVRTQSE 308
                                ||:.....|.|.....||:|    .|.||.:    |.....|...
  Fly   147 --------------------PSANSAANSAANNTTAAAMT----AVNNGIS----GGTFTYTNMT 183

Human   309 ESRPQSLQQPATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKR 373
            |.......:|....:....:|.....|.:....|:|               :|||.|||:||:::
  Fly   184 EGFSVIKDEPVNQASSPTVNPIDMEAQEKIKLERKR---------------QRNRVAASKCRKRK 233

Human   374 KVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAH--KDCPV-------TAMQKKSGY 429
            ...:..||.:.:.|...|..|.|.|..|::.||||||.::.|  ..|.|       ..::..:|.
  Fly   234 LERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGCTVPPNSTDQXHLELSAGE 298

Human   430 HTADKDDSSEDISVPSSPH-------TEAIQHSSVSTSNGVSSTSKAEAVATSVLTQMADQSTEP 487
            :  |::|.:.:...||:|.       .|....:|........|.|:..::..|.|.:....:.:|
  Fly   299 N--DEEDVALETETPSNPEDPEQPMPLEFFSSASTGALELEGSASQDISLTNSELLEEESDNEQP 361

Human   488 ALSQIV 493
            .:..|:
  Fly   362 LVLYIL 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATF2	NP_001243019.1	Nuclear export signal 1 (N-NES)	1..7
		C2H2 Zn finger	27..49	CDD:275370
		GCN4_cent	65..102	CDD:213399
		Herpes_BLLF1	<90..342	CDD:282904	45/227 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..155		7/26 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..373		26/113 (23%)
		Essential for its histone acetyltransferase activity	296..299		0/2 (0%)
		bZIP_ATF2	354..414	CDD:269835	22/59 (37%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	354..374		8/19 (42%)
		coiled coil	355..406	CDD:269835	16/50 (32%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	380..408		10/27 (37%)
		Nuclear export signal 2 (C-NES)	405..414		6/8 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..472		10/53 (19%)
Jra	NP_001260844.1	Jun	<76..>144	CDD:281890	15/67 (22%)
		bZIP_Jun	214..274	CDD:269844	24/74 (32%)
		coiled coil	215..266	CDD:269844	18/65 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910