Protein Alignment Epn2 and lqfR

DIOPT Version :9

• Sequence 1: NP_001349514.1
• Gene: Epn2 / 13855
• MGIID: 1333766
• Length: 652
• Species: Mus musculus
• Sequence 2: NP_732736.2
• Gene: lqfR / 42632
• FlyBaseID: FBgn0261279
• Length: 1415
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 165/639 - (25%)
• Similarity: 276/639 - (43%)
• Gaps: 146/639 - (22%)

Mouse     9 QMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKR-LNDHGKNWR 72
            ::.|:|.||:|.|.||||||::|||||:..||.|:|..|::...|.|:|||:||| |.|:..|||
  Fly    17 KVTNVVMNYTETEGKVREATNDDPWGPTGPLMQELAYSTFSYETFPEVMSMLWKRMLQDNKTNWR 81

Mouse    73 HVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDE 137
            ..||:|.||:||::.|||||....||:|:.:::|:::.:.|..|||||||||.|.::|:..::|:
  Fly    82 RTYKSLLLLNYLVRNGSERVVTSSREHIYDLRSLENYTFTDEGGKDQGINVRHKVRELIDFIQDD 146

Mouse   138 ERLKVERVQALKTKER---MAQVATGV---GSNQITFGRGSSQPNLSTSYSEQEYGKAGGSPASY 196
            :||:.||.:|.|.|::   |:..|.|:   |.:..:.|.|..... |..|::.:|..:.|.  ::
  Fly   147 DRLREERKKAKKNKDKYIGMSSDAMGMRSGGYSGYSGGSGGGGGG-SGGYNDGDYRSSRGD--NW 208

Mouse   197 HGSPEASL-----CPQHRTGAMLGQSEELQPLSQRHPCLPHLGLASHPNGDWAQPCLTCDRAARA 256
            :....|..     ...|..|...| |:...|..:|          ::...|            ||
  Fly   209 YSDKSADKDRYEDDDTHYDGEREG-SDSDSPSPRR----------NYRYND------------RA 250

Mouse   257 TSPRVSSELEQARPQTSGEEELQLQL-ALAMSREVAEQSSESVQTARGSKEERLRRGDDLRLQMA 320
            :...|:||   |:|.:     |.:.: :..:|..|::|.:.:........::::..|........
  Fly   251 SPAEVASE---AKPSS-----LNMNIRSKTVSSPVSKQPTSTASAKPALSQKKIDLGAAANFGKP 307

Mouse   321 L--------EESRRDTVKVPKKKEAKACCKP------GSHSQQTTLLDLMDAL---PSSGPVTQK 368
            .        ..:.|||   |...:......|      .:::.|:...||:|.|   .|..|..:|
  Fly   308 APGGAAGIHSPTHRDT---PTSVDLMGGASPSPSTSKANNNTQSNNNDLLDDLFKTCSPPPGQEK 369

Mouse   369 T--------------EPWSAGASANQ----TNPWGGTVAPSNITDPWPSFGTKPAASVDPW---- 411
            |              .|.::.||..:    .:.:|...|.|.|::| ||.|..|||: |.:
  Fly   370 TLNSAAVIVDDDDDFNPRASDASQQEFGDFASAFGQPSAGSTISEP-PSTGLVPAAN-DEFADFA 432

Mouse   412 ---GVPTTAST-------QSVPKNSDPWAASQQPASNAGKTTDAWGAAKPSSASGSFELFSNFNG 466
               |..|:.|.       .:.|.|......:..|.|.|..||    |....:..|...:..:...
  Fly   433 AFQGSTTSTSALDGNLLKTATPANDSFDLFNSAPTSTAAATT----ATDLLAGLGDLSIHQSMPM 493

Mouse   467 TVKDDFSEFDNLRTSKKPAESGASVPPQDSRTTS--------PDLFESQSLTSA----------- 512
            .|::..:..::..:|..|.      ||.::...:        .||.:.||.::.
  Fly   494 AVEEQLASSNDSMSSASPQ------PPSEAMRLAFSKAQKQLRDLMQVQSASAVAQVAAILGELH 552

Mouse   513 SSKPSSARKTPESFLGPN--------------AALVN-LDSLVTKPAP-PAQSL 550
            :|.......|||..:|.:              |||:| |..|.::..| |:|.:
  Fly   553 NSNALPGFTTPEQLVGLDRQTCDWTCLAHGEYAALLNQLTELFSQDWPEPSQDV 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Epn2	NP_001349514.1	ENTH_Epsin	19..141	CDD:340787	61/122 (50%)
lqfR	NP_732736.2	ENTH_epsin	27..150	CDD:239627	61/122 (50%)
		DUF4045	<226..459	CDD:289995	52/268 (19%)
		Telomere_reg-2	1072..1184	CDD:287202

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2102
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940