Protein Alignment HGSNAT and Hgsnat

DIOPT Version :10

• Sequence 1: XP_005273466.1
• Gene: HGSNAT / 138050
• HGNCID: 26527
• Length: 672
• Species: Homo sapiens
• Sequence 2: NP_084160.2
• Gene: Hgsnat / 52120
• MGIID: 1196297
• Length: 624
• Species: Mus musculus
• Alignment Length: 670
• Identity: 513/670 - (76%)
• Similarity: 553/670 - (82%)
• Gaps: 47/670 - (7%)

Human     3 GAGRALAALLLAASVLSAALLAPGGSSGRDAQAAPPRDLDKKRHAELKMDQALLLIHNELLWTNL 67
            |||.||||||||.|||||.|||||       :.|.| |||:||:.||||||||||||||||.|:|
Mouse     2 GAGPALAALLLAGSVLSATLLAPG-------RRAEP-DLDEKRNVELKMDQALLLIHNELLGTSL 58

Human    68 TVYWKSECCYHCLFQVLVNVPQSPKAGKPSAAAASVSTQHGSILQLNDTLEEKEVCRLEYRFGEF 132
            ||||||:.||.|.||.|.||....|..|||.|..|||||||||||:|.|.||:..|||||:||||
Mouse    59 TVYWKSDDCYQCTFQPLANVSHGGKPAKPSVAPVSVSTQHGSILQVNSTSEERAACRLEYKFGEF 123

Human   133 GNYSLLVKNIHNGVSEIACDLAVNEDPVDSNLPVSIAFLIGLAVIIVISFLRLLLSLDDFNNWIS 197
            |||||||::..:|.::||||:.|||:|||||||||||||:|||:|:.:|.|||||||||.|||||
Mouse   124 GNYSLLVQHASSGANKIACDIIVNENPVDSNLPVSIAFLVGLALIVAVSLLRLLLSLDDVNNWIS 188

Human   198 KAISSRETDRLINSELGSPSRTDPLDGDVQPATWRLSALPPRLRSVDTFRGIALILMVFVNYGGG 262
            |.|:|||||||||||||||||.|||..|.||.|.|.||  .|||.||||||:||:||||||||||
Mouse   189 KTIASRETDRLINSELGSPSRADPLSADYQPETRRSSA--NRLRCVDTFRGLALVLMVFVNYGGG 251

Human   263 KYWYFKHASWNGLTVADLVFPWFVFIMGSSIFLSMTSILQRGCSKFRLLGKIAWRSFLLICIGII 327
            |||||||:||||||||||||||||||||:||||||||||||||||.:|||||.||||||||||:|
Mouse   252 KYWYFKHSSWNGLTVADLVFPWFVFIMGTSIFLSMTSILQRGCSKLKLLGKIVWRSFLLICIGVI 316

Human   328 IVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAVLELLFAKPVPEHCASERSCLSLRDITSSWPQ 392
            ||||||||||||||||||||||||||||||||||||..|.||||:.|..|.||.|||||||||||
Mouse   317 IVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAVLEFFFWKPVPDSCTLESSCFSLRDITSSWPQ 381

Human   393 WLLILVLEGLWLGLTFLLPVPGCPTGYLGPGGIGDFGKYPNCTGGAAGYIDRLLLGDDHLYQHPS 457
            ||.||.||.:||.|||.||||||||||||||||||.||||:||||||||||||||||:|||||||
Mouse   382 WLTILTLESIWLALTFFLPVPGCPTGYLGPGGIGDLGKYPHCTGGAAGYIDRLLLGDNHLYQHPS 446

Human   458 SAVLYHTEVAYDPEGILGTINSIVMAFLGVQCCPDWVTKQACLTEPLSPLWRILFGPCLEVRATE 522
            |.|||||||||||||:||||||||||||||
Mouse   447 STVLYHTEVAYDPEGVLGTINSIVMAFLGV----------------------------------- 476

Human   523 PAQAGKILLYYKARTKDILIRFTAWCCILGLISVALTKVSENEGFIPVNKNLWSLSYVTTLSSFA 587
              ||||||:|||.:||.||.||.||||||||||:.|||||.||||||:||||||:|||||||.||
Mouse   477 --QAGKILVYYKDQTKAILTRFAAWCCILGLISIVLTKVSANEGFIPINKNLWSISYVTTLSCFA 539

Human   588 FFILLVLYPVVDVKGLWTGTPFFYPGMNSILVYVGHEVFENYFPFQWKLKDNQSHKEHLTQNIVA 652
            |||||:||||||||||||||||||||||||||||||||.||||||||||.|.|||||||.|||||
Mouse   540 FFILLILYPVVDVKGLWTGTPFFYPGMNSILVYVGHEVLENYFPFQWKLADEQSHKEHLIQNIVA 604

Human   653 TALWVLIAYILYRKKIFWKI 672
            |||||||||:||:||:||||
Mouse   605 TALWVLIAYVLYKKKLFWKI 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGSNAT	XP_005273466.1	COG4299	237..672	CDD:443440	346/434 (80%)
Hgsnat	NP_084160.2	COG4299	225..624	CDD:443440	348/437 (80%)