Protein Alignment HGSNAT and Hgsnat

DIOPT Version :10

• Sequence 1: XP_005273466.1
• Gene: HGSNAT / 138050
• HGNCID: 26527
• Length: 672
• Species: Homo sapiens
• Sequence 2: NP_001389399.1
• Gene: Hgsnat / 361165
• RGDID: 1560755
• Length: 626
• Species: Rattus norvegicus
• Alignment Length: 670
• Identity: 525/670 - (78%)
• Similarity: 564/670 - (84%)
• Gaps: 45/670 - (6%)

Human     3 GAGRALAALLLAASVLSAALLAPGGSSGRDAQAAPPRDLDKKRHAELKMDQALLLIHNELLWTNL 67
            |||.|||.||||.|||||.|||||       :.|.| |||:||:.||||||||||||||||.|:|
  Rat     2 GAGPALALLLLAGSVLSATLLAPG-------RRAEP-DLDEKRNVELKMDQALLLIHNELLGTSL 58

Human    68 TVYWKSECCYHCLFQVLVNVPQSPKAGKPSAAAASVSTQHGSILQLNDTLEEKEVCRLEYRFGEF 132
            |:|||||.||.|.||.|.||....|..|||..|.|||||||||||:|.||||:..|||||:||||
  Rat    59 TIYWKSEYCYQCTFQPLANVSHGRKPAKPSVEAVSVSTQHGSILQVNSTLEERAACRLEYKFGEF 123

Human   133 GNYSLLVKNIHNGVSEIACDLAVNEDPVDSNLPVSIAFLIGLAVIIVISFLRLLLSLDDFNNWIS 197
            |||||||::..:|..:|||||.|||:|||||||||||||:|||::|.||.|:|||||||.|||||
  Rat   124 GNYSLLVRHASSGADDIACDLVVNENPVDSNLPVSIAFLVGLALVIAISILKLLLSLDDINNWIS 188

Human   198 KAISSRETDRLINSELGSPSRTDPLDGDVQPATWRLSALPPRLRSVDTFRGIALILMVFVNYGGG 262
            |||:|||||||||||||||||.|||..|.||.|.|.||||.|||.||||||:|||||||||||||
  Rat   189 KAIASRETDRLINSELGSPSRADPLGADCQPETRRASALPHRLRCVDTFRGVALILMVFVNYGGG 253

Human   263 KYWYFKHASWNGLTVADLVFPWFVFIMGSSIFLSMTSILQRGCSKFRLLGKIAWRSFLLICIGII 327
            |||||||:|||||||||||||||||||||||||||||:|||||||.:||||||||||||||||||
  Rat   254 KYWYFKHSSWNGLTVADLVFPWFVFIMGSSIFLSMTSLLQRGCSKIKLLGKIAWRSFLLICIGII 318

Human   328 IVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAVLELLFAKPVPEHCASERSCLSLRDITSSWPQ 392
            |||||||||||||||||||||||||||||||||:|||.|.||||:.|..||||||||||||||||
  Rat   319 IVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAMLELFFWKPVPDSCTLERSCLSLRDITSSWPQ 383

Human   393 WLLILVLEGLWLGLTFLLPVPGCPTGYLGPGGIGDFGKYPNCTGGAAGYIDRLLLGDDHLYQHPS 457
            ||:||:||.:||.|||.||||||||||||||||||.||||:||||||||||||||||.|||||||
  Rat   384 WLIILILESIWLALTFFLPVPGCPTGYLGPGGIGDLGKYPHCTGGAAGYIDRLLLGDSHLYQHPS 448

Human   458 SAVLYHTEVAYDPEGILGTINSIVMAFLGVQCCPDWVTKQACLTEPLSPLWRILFGPCLEVRATE 522
            |||||||||||||||:||||||||||||||
  Rat   449 SAVLYHTEVAYDPEGVLGTINSIVMAFLGV----------------------------------- 478

Human   523 PAQAGKILLYYKARTKDILIRFTAWCCILGLISVALTKVSENEGFIPVNKNLWSLSYVTTLSSFA 587
              ||||||||||.:||.|||||.||||||||||:||||:|.||||||:||||||:|||||||.||
  Rat   479 --QAGKILLYYKDQTKAILIRFAAWCCILGLISIALTKMSANEGFIPINKNLWSISYVTTLSCFA 541

Human   588 FFILLVLYPVVDVKGLWTGTPFFYPGMNSILVYVGHEVFENYFPFQWKLKDNQSHKEHLTQNIVA 652
            |.|||:||||||||||||||||||||||||||||||||||:||||||||:|.|||||||.|||||
  Rat   542 FSILLILYPVVDVKGLWTGTPFFYPGMNSILVYVGHEVFEDYFPFQWKLEDEQSHKEHLIQNIVA 606

Human   653 TALWVLIAYILYRKKIFWKI 672
            ||||||||||||:||:||||
  Rat   607 TALWVLIAYILYKKKVFWKI 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGSNAT	XP_005273466.1	COG4299	237..672	CDD:443440	355/434 (82%)
Hgsnat	NP_001389399.1	COG4299	228..626	CDD:443440	355/434 (82%)