Protein Alignment HGSNAT and hgsnat

DIOPT Version :10

• Sequence 1: XP_005273466.1
• Gene: HGSNAT / 138050
• HGNCID: 26527
• Length: 672
• Species: Homo sapiens
• Sequence 2: XP_002934053.2
• Gene: hgsnat / 100485725
• XenbaseID: XB-GENE-984404
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 661
• Identity: 354/661 - (53%)
• Similarity: 462/661 - (69%)
• Gaps: 44/661 - (6%)

Human    12 LLAASVLSAALLAPGGSSGRDAQAAPPRDLDKKRHAELKMDQALLLIHNELLWTNLTVYWKSECC 76
            ||..|.||..||   |:....:..:.|.....:|.:.||||||||||:|.|......|||:|:.|
 Frog    17 LLIVSALSMILL---GTCTSSSLISLPAQNVLRRPSHLKMDQALLLINNALHHEGFVVYWRSDQC 78

Human    77 YHCLFQVLVNVPQSPKAGKPSAAAASVSTQHGSILQLNDTLEEKEVCRLEYRFGEFGNYSLLVKN 141
            |.||:|.||.:..|.:.|  :...|.:.|||...|.|||:..:||:|::.|.|.|||||||.||:
 Frog    79 YQCLYQTLVRIGASKQNG--NQVTAVIETQHPVTLLLNDSSGQKELCQMHYHFREFGNYSLWVKS 141

Human   142 IHNGVSEIACDLAVNEDPVDSNLPVSIAFLIGLAVIIVISFLRLLLSLDDFNNWISKAISSRETD 206
            ..:....:.|::.:|::|..|.:|:.||.|..:.:||::..::.||.|....||:.|.::..|||
 Frog   142 NLSSSDNVTCEIIINQNPAYSYIPILIAVLTYMGLIIIVFVVKFLLRLTLVRNWLYKKMNPIETD 206

Human   207 RLINSELGSPSRTDPLDGDVQPATWRLSALPPRLRSVDTFRGIALILMVFVNYGGGKYWYFKHAS 271
            ||:|||||||:|.|....:.....|..|.  .||||:|||||:||.:|||||||||.||:|||.|
 Frog   207 RLVNSELGSPNRADISSQETYSRAWNPSV--QRLRSLDTFRGLALTIMVFVNYGGGGYWFFKHQS 269

Human   272 WNGLTVADLVFPWFVFIMGSSIFLSMTSILQRGCSKFRLLGKIAWRSFLLICIGIIIVNPNYCLG 336
            |||||||||||||||||||:||:||:.|:|.:|.|::.||||:.|||..|..||:.::|.|||.|
 Frog   270 WNGLTVADLVFPWFVFIMGTSIYLSLNSMLSKGSSRWNLLGKVLWRSVQLFLIGLFVINVNYCRG 334

Human   337 PLSWDKVRIPGVLQRLGVTYFVVAVLELLFAKPVPEHCASERSCLSLRDITSSWPQWLLILVLEG 401
            |||:.::||.||||||.:||..|:.|||:|:||.|:.....|:|..|:|:.|.||:|::||.||.
 Frog   335 PLSFSEIRIMGVLQRLSLTYLAVSALELIFSKPTPDALTQSRTCFLLQDVLSHWPKWIVILALEA 399

Human   402 LWLGLTFLLPVPGCPTGYLGPGGIGDFGKYPNCTGGAAGYIDRLLLGDDHLYQHPSSAVLYHTEV 466
            :||.||.||.||.||.|||||||||||||:|||||||||||||::||..|:||||:|.|:|.:.:
 Frog   400 VWLCLTLLLQVPDCPLGYLGPGGIGDFGKFPNCTGGAAGYIDRMILGQGHIYQHPTSNVIYKSTM 464

Human   467 AYDPEGILGTINSIVMAFLGVQCCPDWVTKQACLTEPLSPLWRILFGPCLEVRATEPAQAGKILL 531
            .|||||:|||||.:||||.|:                                     |||.||:
 Frog   465 PYDPEGLLGTINCVVMAFFGL-------------------------------------QAGIILV 492

Human   532 YYKARTKDILIRFTAWCCILGLISVALTKVSENEGFIPVNKNLWSLSYVTTLSSFAFFILLVLYP 596
            .||.:.|.:|:||.:|..|:|::|..|||.|.|||.|||||||||:||:||||.||:|:|:::|.
 Frog   493 LYKNQHKYVLVRFFSWAIIMGVLSAVLTKCSTNEGIIPVNKNLWSVSYITTLSCFAYFLLMLIYF 557

Human   597 VVDVKGLWTGTPFFYPGMNSILVYVGHEVFENYFPFQWKLKDNQSHKEHLTQNIVATALWVLIAY 661
            :||||.||:|.||:||||||||||||||||||||||:|:::|:|||.||||||::||:|||||:|
 Frog   558 LVDVKKLWSGAPFYYPGMNSILVYVGHEVFENYFPFKWQMQDSQSHAEHLTQNLLATSLWVLISY 622

Human   662 ILYRKKIFWKI 672
            |||||||||||
 Frog   623 ILYRKKIFWKI 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGSNAT	XP_005273466.1	COG4299	237..672	CDD:443440	263/434 (61%)
hgsnat	XP_002934053.2	COG4299	236..633	CDD:443440	263/433 (61%)