Protein Alignment HGSNAT and hgsnat

DIOPT Version :10

• Sequence 1: XP_005273466.1
• Gene: HGSNAT / 138050
• HGNCID: 26527
• Length: 672
• Species: Homo sapiens
• Sequence 2: XP_002660455.3
• Gene: hgsnat / 100329505
• ZFINID: ZDB-GENE-140106-144
• Length: 621
• Species: Danio rerio
• Alignment Length: 661
• Identity: 342/661 - (51%)
• Similarity: 441/661 - (66%)
• Gaps: 51/661 - (7%)

Human    13 LAASVLSAALLAPGGSSGRDAQAAPPRDLDKKRHAELKMDQALLLIHNELLWTNLTVYWKSECCY 77
            :.|.::....:.....:.|.|.:.|.|     :.:.||||:|.|.:.|| :...:.:|..|:.||
Zfish    11 ICAVIVFLIAICAAHMTDRPASSRPHR-----KTSVLKMDEAALSVINE-VEEEMVLYVLSDHCY 69

Human    78 HCLFQVLVNVPQSPKAGKPSAAAASVSTQHGSILQLNDTLEEKEVCRLEYRFGEFGNYSLLVKNI 142
            .||.|.|..:|..|.:|.|::....|.|||...|.:|.|...:: |::.:.|||.|||||.|||:
Zfish    70 QCLPQPLGMIPARPTSGTPASVGFVVGTQHALTLLINSTTTPQQ-CKVNFHFGEQGNYSLWVKNL 133

Human   143 HNGVSEIACDLAVNEDPVDSNLPVSIAFLIGLAVIIVISFLRLLLSLDDFNNWISKAISSRETDR 207
             |..|:|.|::..:.||::|.||:..|||:...:..:.:....:..||...|.:.:...:.||:|
Zfish   134 -NEPSQINCEMITDSDPINSYLPILFAFLVFAFLAALSAIWSTVKRLDAVTNLLIRLGGTVETER 197

Human   208 LINSELGSPSR-TDPLDGDVQPATWRLSALPPRLRSVDTFRGIALILMVFVNYGGGKYWYFKHAS 271
            |||||||:|:| .|.....:.|||     ...||||:|||||::|::|||||||||:||:|:|.|
Zfish   198 LINSELGTPNRLVDASTESIIPAT-----TGRRLRSLDTFRGLSLVIMVFVNYGGGRYWFFRHES 257

Human   272 WNGLTVADLVFPWFVFIMGSSIFLSMTSILQRGCSKFRLLGKIAWRSFLLICIGIIIVNPNYCLG 336
            |||||||||||||||||||:||.||::..|:||..:..||.|:.|||..|..||:||:|||||.|
Zfish   258 WNGLTVADLVFPWFVFIMGTSIGLSLSGSLRRGVKRTHLLWKVFWRSLQLFLIGVIIINPNYCQG 322

Human   337 PLSWDKVRIPGVLQRLGVTYFVVAVLELLFAKPVPEHCASERSCLSLRDITSSWPQWLLILVLEG 401
            |||||.:||||||||||.||.:||.|:|..:.....:.:||.....:.||...||.||.:::||.
Zfish   323 PLSWDSLRIPGVLQRLGFTYLIVAALDLAVSPDRLTNLSSETCWYWVHDICLYWPAWLCVIILET 387

Human   402 LWLGLTFLLPVPGCPTGYLGPGGIGDFGKYPNCTGGAAGYIDRLLLGDDHLYQHPSSAVLYHTEV 466
            :||.||||||||||||||||||||||||:|.||||||||||||.||.|:|:||.|||.|||.|.:
Zfish   388 VWLCLTFLLPVPGCPTGYLGPGGIGDFGQYQNCTGGAAGYIDRWLLKDNHIYQTPSSRVLYLTTM 452

Human   467 AYDPEGILGTINSIVMAFLGVQCCPDWVTKQACLTEPLSPLWRILFGPCLEVRATEPAQAGKILL 531
            .:||||:||:||||:|||||:                                     |||||||
Zfish   453 PFDPEGVLGSINSILMAFLGL-------------------------------------QAGKILL 480

Human   532 YYKARTKDILIRFTAWCCILGLISVALTKVSENEGFIPVNKNLWSLSYVTTLSSFAFFILLVLYP 596
            :|:.:.:.|:.||..|..|||:||..|||.|.|:|||||||||||||||||||.|||..|:..|.
Zfish   481 HYRDQHRQIITRFLMWGLILGIISAVLTKCSRNDGFIPVNKNLWSLSYVTTLSCFAFVALVFFYY 545

Human   597 VVDVKGLWTGTPFFYPGMNSILVYVGHEVFENYFPFQWKLKDNQSHKEHLTQNIVATALWVLIAY 661
            .||||..|:|.||||||||||||||||||||.||||:||:.::|||.|||.||::||::||.||:
Zfish   546 TVDVKKWWSGAPFFYPGMNSILVYVGHEVFEEYFPFRWKMANSQSHTEHLAQNLLATSIWVFIAF 610

Human   662 ILYRKKIFWKI 672
            :||||||||||
Zfish   611 LLYRKKIFWKI 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGSNAT	XP_005273466.1	COG4299	237..672	CDD:443440	265/434 (61%)
hgsnat	XP_002660455.3	COG4299	225..621	CDD:443440	265/432 (61%)