| Sequence 1: | NP_653252.4 | Gene: | PXDNL / 137902 | HGNCID: | 26359 | Length: | 1463 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_523891.2 | Gene: | Pxn / 38326 | FlyBaseID: | FBgn0011828 | Length: | 1527 | Species: | Drosophila melanogaster |
| Alignment Length: | 1535 | Identity: | 591/1535 - (38%) |
|---|---|---|---|
| Similarity: | 833/1535 - (54%) | Gaps: | 120/1535 - (7%) |
- Green bases have known domain annotations that are detailed below.
|
Human 11 LFLLAGWCLPGLPCPSRCLCFKSTVRCMHLMLDHIPQVPQQTTVLDLRFNRIREIPGSAFKKLKN 75
Human 76 LNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYIHFNQLEMLQPE 140
Human 141 TFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDSNALVCDCDLMWLGELLQGFAQHGHTQ 205
Human 206 AAATCEYPRRLHGRAVASVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHN 270
Human 271 NHSLDLEDDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRY------------ 323
Human 324 ---------------------SSLPAKPSFVIQPQDTEVLIGTS--TTLECMATGHPHPLITWTR 365
Human 366 DNG---LELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKD 427
Human 428 QVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLP-------VEGQHTVLSSGTLRIDRAAQHDQGQ 485
Human 486 YECQAVSSLGVKKVSVQLTVK------PKALAVFTQLPQDTSVEVGKNINISCHA-QGEPQPIIT 543
Human 544 WNKEG------VQITESGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQG 602
Human 603 RQAGDDFVESSILDAVQRVDSAINSTRRHLFSQK----PHTSSDLLAQFHYPRDPLIVEMARAGE 663
Human 664 IFEHTLQLIRERVKQGLTVDLEGKEFRYNDLVSPRSLSLIANLSGCTARRPLPNCSNRCFHAKYR 728
Human 729 AHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVG-------SRQPLPPPRLVATV 786
Human 787 WARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHAD 851
Human 852 PRGTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVP 916
Human 917 RGLLKTGFPWPPSGKPLLPFSTGPP-TECAR--QEQESPCFLAGDHRANEHLALAAMHTLWFREH 978
Human 979 NRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAG 1043
Human 1044 IINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVA 1108
Human 1109 AKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQN 1173
Human 1174 EIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPG 1238
Human 1239 VFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQDCCADC- 1302
Human 1303 ----------------RSRGQFRAVTQESQKKRSAQ-YSYPVDKDMELSHLRSRQQDKIYVGEDA 1350
Human 1351 RNVTVLAK--TKFSQDFSTFAAEIQETITALREQINKLEARLRQAGCTDVRGVPRKAEERWMKED 1413
Human 1414 CTHCICESGQVTCVVEICPPAPCP---SPELVKGTCCPVC 1450 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PXDNL | NP_653252.4 | LRR 1 | 51..72 | 12/20 (60%) | |
| leucine-rich repeat | 52..85 | CDD:275378 | 18/32 (56%) | ||
| LRR_8 | 53..134 | CDD:316378 | 30/80 (38%) | ||
| LRR 2 | 75..96 | 7/20 (35%) | |||
| leucine-rich repeat | 86..123 | CDD:275378 | 9/36 (25%) | ||
| LRR 3 | 99..120 | 6/20 (30%) | |||
| LRR_8 | 123..182 | CDD:316378 | 25/58 (43%) | ||
| LRR 4 | 123..144 | 5/20 (25%) | |||
| leucine-rich repeat | 124..147 | CDD:275378 | 6/22 (27%) | ||
| LRR 5 | 147..168 | 10/20 (50%) | |||
| leucine-rich repeat | 148..171 | CDD:275378 | 10/22 (45%) | ||
| leucine-rich repeat | 172..184 | CDD:275378 | 9/11 (82%) | ||
| LRRCT | 180..232 | CDD:214507 | 12/51 (24%) | ||
| Ig_3 | 234..309 | CDD:316449 | 29/74 (39%) | ||
| Ig_3 | 329..402 | CDD:316449 | 25/77 (32%) | ||
| Ig | 432..505 | CDD:325142 | 26/79 (33%) | ||
| Ig | 528..596 | CDD:325142 | 25/74 (34%) | ||
| peroxidasin_like | 851..1286 | CDD:188658 | 227/437 (52%) | ||
| VWC | 1400..1450 | CDD:214564 | 20/52 (38%) | ||
| Pxn | NP_523891.2 | LRR_RI | 51..>161 | CDD:238064 | 43/109 (39%) |
| leucine-rich repeat | 54..77 | CDD:275380 | 13/22 (59%) | ||
| LRR_8 | 55..112 | CDD:290566 | 25/56 (45%) | ||
| leucine-rich repeat | 78..101 | CDD:275380 | 9/22 (41%) | ||
| leucine-rich repeat | 102..125 | CDD:275380 | 6/22 (27%) | ||
| LRR_8 | 124..184 | CDD:290566 | 25/59 (42%) | ||
| leucine-rich repeat | 126..149 | CDD:275380 | 6/22 (27%) | ||
| LRR_4 | 148..185 | CDD:289563 | 20/36 (56%) | ||
| leucine-rich repeat | 150..173 | CDD:275380 | 10/22 (45%) | ||
| Ig | 240..325 | CDD:299845 | 33/84 (39%) | ||
| IG_like | 242..325 | CDD:214653 | 33/82 (40%) | ||
| I-set | 366..450 | CDD:254352 | 30/84 (36%) | ||
| Ig | 384..451 | CDD:143165 | 24/67 (36%) | ||
| I-set | 458..546 | CDD:254352 | 30/94 (32%) | ||
| Ig | 472..536 | CDD:299845 | 23/68 (34%) | ||
| I-set | 553..644 | CDD:254352 | 29/95 (31%) | ||
| Ig | 570..643 | CDD:299845 | 25/74 (34%) | ||
| An_peroxidase | 777..1317 | CDD:281139 | 278/547 (51%) | ||
| peroxidasin_like | 898..1338 | CDD:188658 | 227/440 (52%) | ||
| VWC | 1465..1523 | CDD:278520 | 22/57 (39%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165150040 | |
| Domainoid | 1 | 1.000 | 667 | 1.000 | Domainoid score | I148 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG2408 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 1154 | 1.000 | Inparanoid score | I209 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG46064 | |
| OrthoDB | 1 | 1.010 | - | - | D276568at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000202 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40686 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105829 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR11475 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X2950 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.770 | |||||