Protein Alignment CPT2 and CPT2

DIOPT Version :10

• Sequence 1: NP_000089.1
• Gene: CPT2 / 1376
• HGNCID: 2330
• Length: 658
• Species: Homo sapiens
• Sequence 2: NP_647756.1
• Gene: CPT2 / 38355
• FlyBaseID: FBgn0035383
• Length: 667
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 295/636 - (46%)
• Similarity: 429/636 - (67%)
• Gaps: 14/636 - (2%)

Human    33 QYLQRSIVPTMHYQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHE 97
            ||||.|.:||:::|.||||||||.||::.||:|.|.||||:..:..:|:|..:.|..|||.|||.
  Fly    29 QYLQCSKLPTLYFQRSLPRLPIPLLENSCRRFLEATKPLLSPAEQAQTQQTVEQFRQGIGMELHA 93

Human    98 QLVALDKQNKHTSYISGPWFDMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRF 162
            :|.:.|.:||||||||.|||||||:.|..:.||:||.:....|.:.||..|:.||||:.:|::||
  Fly    94 KLKSHDAENKHTSYISQPWFDMYLADRAPLPLNYNPLLVMKSDARPEYQQQVVRATNLIISSLRF 158

Human   163 LKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLP 227
            .::|:|.||||||:|:|..||||.:::|.::..|.:.:.|.:|...|:|||||||.|||.::|:|
  Fly   159 WRSLQADLLEPEVYHMNAKKSDTSSYRRWMKVAPKAFATYASYAFKAFPLDMSQYNRLFGTSRIP 223

Human   228 KPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILS-DSS-PAPEFPLAY 290
            :..:|||.....|:|:||:|:|:.|..:|||..|.|.|||.|...|:.:|. |:. .|...||..
  Fly   224 RIGKDELVQSPDAKHILVMRRGHMYAVNVLDSSGYIESPSVILGRLRAVLKLDADREAASVPLGV 288

Human   291 LTSENRDIWAELRQKLMSSGNEESL--RKVDSAVFCLCLDD-----FPIKDLVHLSHNMLHGDGT 348
            |||..||.||:.||..:|:.....|  |:||:|:||:|||.     |.......|..::|.|...
  Fly   289 LTSGQRDEWAKTRQHFVSNTKNADLLEREVDAALFCVCLDGEEDGVFNENQQEPLLKHLLAGKAQ 353

Human   349 NRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQS--QPATTDSTVT 411
            |||||||.:|:|:.||:||::|||||||||||||:|||::||:.:.|.|:.::  .||..|.: .
  Fly   354 NRWFDKSISLLISADGTTAINFEHSWGDGVAVLRYFNELYKDTLKQPFVSTETVHTPAEGDFS-N 417

Human   412 VQKLNFELTDALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFL 476
            |:.:|||:.||.|:.::.|..|..:.:..|.::.:::....|...|:..||||::.||:||:|:.
  Fly   418 VRPINFEIDDATKSAVSEAYNKNASIVDNLDMNVLKYPHINKPTCKQYGLSPDSIIQLSFQLAYR 482

Human   477 RQYGQTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVR-EPSRHSAGELQQMMVECSKYHG 540
            :.|...|.:||||||:||:||||||:||.:..|:...||.:: |.|:.|||||:.|:..|||.||
  Fly   483 QAYSGYVGSYESCSTSAFRHGRTETMRPCTNATRDFCEAILQPERSKPSAGELRAMIDNCSKVHG 547

Human   541 QLTKEAAMGQGFDRHLFALRHLAAAKGIILPELYLDPAYGQINHNVLSTSTLSSPAVNLGGFAPV 605
            |||||||||||||||||||||.|..:||.:|:||...||.:||:|::|||||.|.|:..|.|.||
  Fly   548 QLTKEAAMGQGFDRHLFALRHTAQKEGIPIPDLYETEAYKRINNNIISTSTLGSDALLAGSFGPV 612

Human   606 VSDGFGVGYAVHDNWIGCNVSSYPGR-NAREFLQCVEKALEDMFDALEGKS 655
            |.:|||:||::.:::.|..|::|..: :.:.|:..:|.|.:.:...::..|
  Fly   613 VKNGFGIGYSIQNDFAGAIVTTYKNQADGKVFIDSLESAFDKICAVIQQSS 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPT2	NP_000089.1	Carn_acyltransf	52..642	CDD:459926	280/602 (47%)
CPT2	NP_647756.1	Carn_acyltransf	48..650	CDD:459926	282/614 (46%)