DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Emb and DIP-eta

DIOPT Version :9

Sequence 1:	NP_034460.3	Gene:	Emb / 13723	MGIID:	95321	Length:	330	Species:	Mus musculus
Sequence 2:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	61/271 - (22%)
Similarity:	104/271 - (38%)	Gaps:	59/271 - (21%)

- Green bases have known domain annotations that are detailed below.

Mouse    76 NVILEKPSHVELKCVYTATKDLNLMNVTWKKDD-EPLE-TTGDFNTTKMGNTLTSQYRFIVFNSK 138
            ::::.:.|:|.|||..|.:.:   ..:||:::. .|:| .||:...:..|..|      ::.|.:
  Fly   155 DMVVREGSNVTLKCAATGSPE---PTITWRRESGVPIELATGEEVMSIEGTDL------VIPNVR 210

Mouse   139 Q--LGKYSCVFG-----EKELRGTFNIHVPKAHGKKKSLIAYV-GDSTVLKCVCQDCLPLNWTWY 195
            :  :|.|.|:..     ....|.|..:|.|.....:..||..| |....|.|. .:..|.:..::
  Fly   211 RHHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCE-SEAYPKSINYW 274

Mouse   196 MGNETAQVPIDAHSNEKYIIN----GSHANETRLKIKHLLEEDGGSYWCRATFQLGESEEQNELV 256
            .......||    ...||..|    |.:.|..||.|..|.:.:.|||.|.|...||:::...:|
  Fly   275 TRERGEIVP----PGGKYSANVTEIGGYRNSMRLHINPLTQAEFGSYRCVAKNSLGDTDGTIKL- 334

Mouse   257 VLSFLVP------LKPFLAILAEVILLVAIILLCEVYTHKKKNDPDAGKEFEQIEQLKSDDSNGI 315
               :.:|      ::.|.|                  .||.|.   ..|..|.....::.:.:|.
  Fly   335 ---YRIPPNAVNYVENFEA------------------RHKGKK---RTKSSESHHPARAQEHSGE 375

Mouse   316 ENNVPRYRKTD 326
            :...|..||.|
  Fly   376 DMENPGKRKAD 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Emb	NP_034460.3	Ig	85..146	CDD:143165	16/64 (25%)
		IG_like	168..257	CDD:214653	26/93 (28%)
		Ig	179..250	CDD:143165	21/74 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..330		7/34 (21%)
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845
		IG_like	51..137	CDD:214653
		IG_like	153..237	CDD:214653	20/90 (22%)
		Ig	161..224	CDD:299845	18/71 (25%)
		IG_like	252..335	CDD:214653	24/91 (26%)
		Ig	258..333	CDD:143165	21/79 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910