DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZNF572 and CG31441

DIOPT Version :9

Sequence 1:	NP_689625.2	Gene:	ZNF572 / 137209	HGNCID:	26758	Length:	529	Species:	Homo sapiens
Sequence 2:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	76/274 - (27%)
Similarity:	132/274 - (48%)	Gaps:	42/274 - (15%)

- Green bases have known domain annotations that are detailed below.

Human    99 IAKEEEKPNHQE-----WDSGEHTN--ACVQQNSSFVDRPYKCSECWKSFSNSSHLRTHQRTHSG 156
            :.:|.:||:.::     ||   ||:  .||                  :.::::.|.  :..|:.
  Fly    94 VDEELDKPDVEKLQQDLWD---HTDQEMCV------------------AMADTAGLL--REDHND 135

Human   157 EKPYKCSECAKCFCNSSHLIQHLRMHTGEKPYQCGECGKSFSNTSHLI------IHERTHTGEKP 215
            .:..|.:|.|.  .|..:..:.:::.|.|..:    |.:...|.|.:.      :.:||....|.
  Fly   136 NEKAKDAEDAT--QNEKNQEEQVQVQTEEVEH----CQEQLHNMSIISKGVSARVPKRTKRNSKS 194

Human   216 YKCPECGKRFSSSSHLIQHHRSHTGEKPYECSVCGKGFSHSYVLIEHQRTHTGEKPYKCPDCGKS 280
            :.|.:||..|.||::|..|.:.|:|.||:.|.:|...:.....:..|:..||..:||.|..|.|:
  Fly   195 WFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDICQAKYYTDNEMRRHRILHTDARPYACRFCSKT 259

Human   281 FSQSSSLIRHQRTHTGEKPYKCLECEKSFGCNSTLIKHQRIHTGEKPYQCPECGKNFSRSSNLIT 345
            :...||.:.|:||||.|:|::|..|:|:|...||..||:.:||.::.|.|..|.:.|.|||:|..
  Fly   260 YRGCSSKVVHERTHTNERPFQCQHCDKAFTSTSTRQKHEMLHTNQRKYHCEICDQWFLRSSHLTL 324

Human   346 HQKMHTGEKSYESS 359
            ||.....::..||:
  Fly   325 HQSTKLHQRRAESA 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZNF572	NP_689625.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62
		COG5048	122..494	CDD:227381	67/244 (27%)
		C2H2 Zn finger	134..154	CDD:275368	1/19 (5%)
		C2H2 Zn finger	162..182	CDD:275368	3/19 (16%)
		C2H2 Zn finger	190..210	CDD:275368	4/25 (16%)
		C2H2 Zn finger	218..238	CDD:275368	8/19 (42%)
		C2H2 Zn finger	246..266	CDD:275368	3/19 (16%)
		C2H2 Zn finger	274..294	CDD:275368	7/19 (37%)
		C2H2 Zn finger	302..322	CDD:275368	8/19 (42%)
		C2H2 Zn finger	330..350	CDD:275368	9/19 (47%)
		C2H2 Zn finger	386..406	CDD:275368
		C2H2 Zn finger	414..434	CDD:275368
		C2H2 Zn finger	442..462	CDD:275368
		C2H2 Zn finger	470..490	CDD:275368
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071
		COG5048	<174..337	CDD:227381	55/162 (34%)
		C2H2 Zn finger	197..217	CDD:275370	8/19 (42%)
		C2H2 Zn finger	225..245	CDD:275368	3/19 (16%)
		C2H2 Zn finger	253..273	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..290	CDD:290200	11/21 (52%)
		C2H2 Zn finger	281..301	CDD:275368	8/19 (42%)
		C2H2 Zn finger	309..328	CDD:275368	9/18 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000