DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Elk1 and Ets97D

DIOPT Version :9

Sequence 1:	NP_031948.4	Gene:	Elk1 / 13712	MGIID:	101833	Length:	429	Species:	Mus musculus
Sequence 2:	NP_001263000.1	Gene:	Ets97D / 43236	FlyBaseID:	FBgn0004510	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	97	Identity:	51/97 - (52%)
Similarity:	65/97 - (67%)	Gaps:	13/97 - (13%)

- Green bases have known domain annotations that are detailed below.

Mouse     1 MDPS------------VTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKT 53
            |:||            |.||||||::|.:..:..:|.|...: |||||.|.:.||||||.:|||.
  Fly   330 MNPSNYTTIGSGNNGQVQLWQFLLEILTDCEHTDVIEWVGTE-GEFKLTDPDRVARLWGEKKNKP 393

Mouse    54 NMNYDKLSRALRYYYDKNIIRKVSGQKFVYKF 85
            .|||:|||||||||||.::|.||||::|.|||
  Fly   394 AMNYEKLSRALRYYYDGDMISKVSGKRFAYKF 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elk1	NP_031948.4	ETS	4..89	CDD:197710	49/94 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	119..146
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	165..204
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	227..253
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	302..354
		Sufficient for interaction with MAD2L2. /evidence=ECO:0000250\|UniProtKB:P19419	350..400
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:288472
		SAM_PNT-GABP-alpha	184..272	CDD:176084
		ETS	345..429	CDD:197710	48/82 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810